• Publications
  • Influence
Amniotic fluid embolism: analysis of the national registry.
The striking similarities between clinical and hemodynamic findings in amniotic fluid embolism and both anaphylaxis and septic shock suggest a common pathophysiologic mechanism for all these conditions. Expand
First-trimester maternal serum PAPP-A and free-beta subunit human chorionic gonadotropin concentrations and nuchal translucency are associated with obstetric complications: a population-based
Low pregnancy-associated plasma protein A levels in the first trimester were associated strongly with a number of adverse pregnancy outcomes, and low free-beta subunit human chorionic gonadotropin levels and large nuchal translucency were both associated with early fetal loss. Expand
Threatened abortion: A risk factor for poor pregnancy outcome, a population-based screening study.
First-trimester vaginal bleeding is an independent risk factor for adverse obstetric outcome that is directly proportional to the amount of bleeding. Expand
Maternal death in the 21st century: causes, prevention, and relationship to cesarean delivery.
Most maternal deaths are not preventable, given the diversity of causes of maternal death, and no systematic reduction in maternal death rate in the United States can be expected unless all women undergoing cesarean delivery receive thromboembolism prophylaxis. Expand
Temporal and demographic trends in cerebral palsy--fact and fiction.
  • S. Clark, G. Hankins
  • Medicine, Psychology
  • American journal of obstetrics and gynecology
  • 1 March 2003
Improved neonatal survival since the 1980s has been associated with a stable or decreasing rate of neurologic impairment and thus could not have obscured improvement from reduced term asphyxia and refutes the hypothesis that increased survival of premature, neurologically impaired infants may have masked an actual reduction in cerebral palsy among term infants. Expand
A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy.
Fetal exposure to magnesium sulfate before anticipated early preterm delivery did not reduce the combined risk of moderate or severe cerebral palsy or death, although the rate of cerebral palsies was reduced among survivors. Expand
A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy
This case-control study was the first to show a decrease in the incidence of cerebral palsy in the offspring of women who were given magnesium sulfate before preterm delivery, and is consistent with previous reports that antenatal magnesium sulfates does not reduce the combined risk of death or moderate or severe cerebral palsies, but may reduce the risk of cortex palsy among survivors. Expand
Structure-Function of the Tumor Suppressor BRCA1
This mini-review examines the structure-function relationships of the BRCA1 protein and the relevance to cancer progression. Expand
Role of human placental apical membrane transporters in the efflux of glyburide, rosiglitazone, and metformin.
The role of placental transporters in the biodisposition of oral hypoglycemic drugs that could be used as monotherapy or in combination therapy for gestational diabetes and administration of drug combinations was determined. Expand