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Medulloblastoma

Known as: Medulloblastomas, BRAIN, MEDULLOBLASTOMA, MEDULLOBLASTOMA, MALIGNANT 
A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
ABSTRACT The development of the nervous system relies on the coordinated regulation of stem cell self-renewal and differentiation… Expand
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Review
2016
Review
2016
The 2016 World Health Organization Classification of Tumors of the Central Nervous System is both a conceptual and practical… Expand
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Highly Cited
2011
Highly Cited
2011
Medulloblastoma, a small blue cell malignancy of the cerebellum, is a major cause of morbidity and mortality in pediatric… Expand
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Highly Cited
2011
Highly Cited
2011
PURPOSE Recent genomic approaches have suggested the existence of multiple distinct subtypes of medulloblastoma. We studied a… Expand
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Highly Cited
2011
Highly Cited
2011
Genomic analysis of a childhood cancer reveals markedly fewer mutations than what is typically seen in adult cancers… Expand
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Highly Cited
2009
Highly Cited
2009
Medulloblastoma is the most common malignant brain tumor in children. Aberrant activation of the hedgehog signaling pathway is… Expand
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Highly Cited
2004
Highly Cited
2004
Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate signaling pathways important for neoplasia, including cell… Expand
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Highly Cited
2002
Highly Cited
2002
Constitutive Hedgehog (Hh) pathway activity is associated with initiation of neoplasia, but its role in the continued growth of… Expand
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Highly Cited
2002
Highly Cited
2002
The sonic hedgehog (SHH) signaling pathway directs the embryonic development of diverse organisms and is disrupted in a variety… Expand
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Highly Cited
1997
Highly Cited
1997
The PATCHED (PTC) gene encodes a Sonic hedgehog (Shh) receptor and a tumor suppressor protein that is defective in basal cell… Expand
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