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Diffuse low-grade and intermediate-grade gliomas (which together make up the lower-grade gliomas, World Health… Expand Glioblastoma multiforme (GBM) comprises several molecular subtypes, including proneural GBM. Most therapeutic approaches… Expand We have profiled promoter DNA methylation alterations in 272 glioblastoma tumors in the context of The Cancer Genome Atlas (TCGA… Expand BACKGROUND
A recent genomewide mutational analysis of glioblastomas (World Health Organization [WHO] grade IV glioma) revealed… Expand Glioblastomas are lethal cancers characterized by florid angiogenesis promoted in part by glioma stem cells (GSCs). Because… Expand OBJECTIVEThere is still no general consensus in the literature regarding the role of extent of glioma resection in improving… Expand Malignant astrocytic gliomas such as glioblastoma are the most common and lethal intracranial tumors. These cancers exhibit a… Expand Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and discovered to resemble stages in… Expand Recent discoveries of endogenous negative regulators of angiogenesis, thrombospondin, angiostatin and glioma-derived angiogenesis… Expand As I have pointed out earlier, when I met Oliver Zangwill in 1961 at a meeting on dyslexia in Baltimore, he listened patiently to… Expand