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Glioblastoma

Known as: Grade IV Astrocytic Neoplasm, WHO Grade IV Glioma, Glioblastoma, NOS 
The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the… 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Cancer at single-cell resolution Single-cell sequencing can illuminate the genetic properties of brain cancers and reveal… 
Highly Cited
2008
Highly Cited
2008
Human cancer cells typically harbour multiple chromosomal aberrations, nucleotide substitutions and epigenetic modifications that… 
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Highly Cited
2008
Highly Cited
2008
Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles… 
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Review
2008
Review
2008
  • P. Wen, S. Kesari
  • The New England journal of medicine
  • 2008
  • Corpus ID: 41225938
Approximately 5% of patients with malignant gliomas have a family history of gliomas. Some of these familial cases are associated… 
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Review
2007
Review
2007
Glioblastoma is the most frequent and most malignant human brain tumor. The prognosis remains very poor, with most patients dying… 
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Highly Cited
2006
Highly Cited
2006
BackgroundRecently, a small population of cancer stem cells in adult and pediatric brain tumors has been identified. Some… 
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Glioblastoma, the most common primary brain tumor in adults, is usually rapidly fatal. The current standard of care… 
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Epigenetic silencing of the MGMT (O6-methylguanine-DNA methyltransferase) DNA-repair gene by promoter methylation… 
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Highly Cited
2005
Highly Cited
2005
MicroRNAs (miRNAs) are small noncoding RNA molecules that regulate protein expression by targeting the mRNA of protein-coding… 
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Highly Cited
2004
Highly Cited
2004
We conducted a population-based study on glioblastomas in the Canton of Zurich, Switzerland (population, 1.16 million) to… 
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