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Glioblastoma

Known as: Grade IV Astrocytic Neoplasm, WHO Grade IV Glioma, Glioblastoma, NOS 
The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the… 
National Institutes of Health

Related topics

Related topics

48 relations
AnaplasiaAnaplastic astrocytomaBlood supply aspectsCarmustine

Broader (4)

AstrocytomaGliomaMalignant neoplasm of braincarcinoma brain

Narrower (1)

Glioblastoma Multiforme

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype.
Glioblastomas are highly infiltrated by diverse immune cells, including microglia, macrophages, and myeloid-derived suppressor… 
Highly Cited
2015
Highly Cited
2015
CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells
Glioblastoma (GB) remains the most aggressive primary brain malignancy. Adoptive transfer of chimeric antigen receptor (CAR… 
Highly Cited
2012
Highly Cited
2012
Glioblastoma survival in the United States before and during the temozolomide era
The standard-of-care treatment for newly diagnosed glioblastoma changed in 2005, when radiation therapy plus temozolomide… 
Highly Cited
2012
Highly Cited
2012
Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells.
Growth of numerous cancer types is believed to be driven by a subpopulation of poorly differentiated cells, often referred to as… 
Review
2011
Review
2011
Current concepts and management of glioblastoma
Glioblastoma is the most common malignant primary brain tumor in adults. Its often rapid clinical course, with many medical and… 
Review
2010
Review
2010
Recent advances in therapy for glioblastoma.
Glioblastoma is the most common primary malignant brain tumor in adults and is a challenging disease to treat. The current… 
Highly Cited
2010
Highly Cited
2010
A chelator-free multifunctional [64Cu]CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy.
We synthesized and evaluated a novel class of chelator-free [(64)Cu]CuS nanoparticles (NPs) suitable both for PET imaging and as… 
Highly Cited
2009
Highly Cited
2009
SOX2 Silencing in Glioblastoma Tumor‐Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity
Glioblastoma, the most aggressive cerebral tumor, is invariably lethal. Glioblastoma cells express several genes typical of… 
Review
2007
Review
2007
Making a tumour's bed: glioblastoma stem cells and the vascular niche
Parallel to the role that normal stem cells play in organogenesis, cancer stem cells are thought to be crucial for tumorigenesis… 
Highly Cited
2007
Highly Cited
2007
Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma
Concurrent temozolomide (TMZ) and radiotherapy is the new standard of care for patients with newly diagnosed glioblastoma. In 51… 
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