Glioblastoma

Known as: Grade IV Astrocytic Neoplasm, WHO Grade IV Glioma, Glioblastoma, NOS 
The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulated in cancers such as in non… (More)
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Review
2017
Review
2017
The wide variety of treatment options that exist for glioblastoma, including surgery, ionizing radiation, anti-neoplastic… (More)
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Review
2017
Review
2017
Glioblastoma (GBM) is a primary neuroepithelial tumor of the central nervous system, characterized by an extremely aggressive… (More)
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Review
2016
Review
2016
BACKGROUND Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults. Current treatment options at… (More)
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Highly Cited
2014
Highly Cited
2014
Human cancers are complex ecosystems composed of cells with distinct phenotypes, genotypes, and epigenetic states, but current… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND In 2004, a randomised phase III trial by the European Organisation for Research and Treatment of Cancer (EORTC) and… (More)
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Highly Cited
2008
Highly Cited
2008
Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Epigenetic silencing of the MGMT (O6-methylguanine-DNA methyltransferase) DNA-repair gene by promoter methylation… (More)
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Highly Cited
2005
Highly Cited
2005
MicroRNAs (miRNAs) are small noncoding RNA molecules that regulate protein expression by targeting the mRNA of protein-coding… (More)
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