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Carmustine

Known as: BCNU (bis chloroethylnitrosourea), Carmustin, bis-chloroethylnitrosourea 
An antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function… 
National Institutes of Health

Related topics

Related topics

43 relations
BAEC protocolBVCPP protocolCarmustine 7.7 MG Drug Implant [Gliadel]Colonic Neoplasms

Narrower (10)

BAVC protocolBCVP protocolBEM protocolBOMES protocol

Broader (1)

Nitrosourea Compounds

Papers overview

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Highly Cited
2008
Highly Cited
2008
Preparation and study of a family of dinuclear Ru(II) complexes that catalyze the decomposition of water.
An approach is developed for the four-electron oxidation of water to provide dioxygen that involves the juxtaposition of two Ru… 
Highly Cited
2005
Highly Cited
2005
Highly efficient access to strained bicyclic ketals via gold-catalyzed cycloisomerization of bis-homopropargylic diols.
A highly efficient gold-catalyzed cycloisomerization reaction of bis-homopropargylic diols is described. The cyclizations are… 
Highly Cited
1999
Highly Cited
1999
Palladium/P,O-Ligand-Catalyzed Suzuki Cross-Coupling Reactions of Arylboronic Acids and Aryl Chlorides. Isolation and Structural Characterization of (P,O)-Pd(dba) Complex.
The phenyl backbone-derived P,O-ligands 1 and 2 were investigated for their utility as ligands in palladium/ligand-catalyzed… 
Review
1997
Review
1997
Molecular mechanisms in retrovirus DNA integration.
Highly Cited
1988
Highly Cited
1988
Measurement of cytotoxicity by target cell release and retention of the fluorescent dye bis-carboxyethyl-carboxyfluorescein (BCECF).
Highly Cited
1985
Highly Cited
1985
The effect of treatment in fractionated schedules with the combination of X-irradiation and six cytotoxic drugs on the RIF-1 tumor and normal mouse skin.
Highly Cited
1985
Highly Cited
1985
Effects of chemotherapeutic drugs on platelet and metastatic tumor cell-endothelial cell interactions as a model for assessing vascular endothelial integrity.
An in vitro assay for examining the sublethal effects of chemotherapeutic agents on vascular endothelial integrity is described… 
Highly Cited
1981
Highly Cited
1981
The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis
Triton X-100 soluble proteins from 125I-labeled human platelets were studied by crossed immunoelectrophoresis employing a… 
Review
1978
Review
1978
Patterns of resistance and therapeutic synergism among alkylating agents.
Alkylating anticancer drugs are varied in chemical structure, alkylating moieties, and likely mechanisms of cytotoxic activity… 
Highly Cited
1977
Highly Cited
1977
Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas
Single agents and combinations of agents were tested for antitumor activity against four transplantable colon tumors in mice. The… 
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