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Carmustine

Known as: BCNU (bis chloroethylnitrosourea), Carmustin, bis-chloroethylnitrosourea 
An antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function… 
National Institutes of Health

Related topics

Related topics

43 relations
BAEC protocolBVCPP protocolCarmustine 7.7 MG Drug Implant [Gliadel]Colonic Neoplasms

Narrower (10)

BAVC protocolBCVP protocolBEM protocolBOMES protocol

Broader (1)

Nitrosourea Compounds

Papers overview

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Highly Cited
1992
Highly Cited
1992
Erfahrungen bei der Entwicklung und Portierung eines elektronischen Leitstands
Der Beitrag gibt einen Bericht uber Erfahrungen, die bei der Entwicklung und Portierung des elektronischen Leitstands L1 in… 
Highly Cited
1985
Highly Cited
1985
Probing different conformational states of bovine alpha-lactalbumin: fluorescence studies with 4,4'-bis[1-(phenylamino)-8-naphthalenesulfonate].
The binding of the fluorescent probe 4,4'-bis[1-(phenylamino)-8-naphthalenesulfonate] (bis-ANS) to bovine alpha-lactalbumin… 
Highly Cited
1979
Highly Cited
1979
Isobologram analysis of X-ray--BCNU interactions in vitro.
9L rat brain tumor cells were exposed for 1 hr to either 1, 3, 5, or 7.5 μg/ml 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU… 
Highly Cited
1976
Highly Cited
1976
The cause of G2-arrest in Chinese hamster ovary cells treated with anticancer drugs.
The nature of G2-arrest was studied in Chinese hamster ovary cells after exposure to 4'-demethyl-epipodophyllotoxin 9-)4,6-0-2… 
Highly Cited
1976
Highly Cited
1976
In vivo clonogenic tumor cell kinetics following 1,3-bis(2-chloroethyl)-1-nitrosourea brain tumor therapy.
An in vitro colony formation assay was modified to determine the effects of in vivo 1,3-bis(2-chloroethyl)-1-nitrosourea therapy… 
Highly Cited
1976
Highly Cited
1976
Structure-function relations in hemoglobin as determined by x-ray absorption spectroscopy.
Conclusions concerning the structure around the iron atom in oxy- and carbonmonoxyhemoglobin have been obtained by fluorescent x… 
Highly Cited
1975
Highly Cited
1975
Comparative effects of three nitrosourea derivatives on mammalian cell cycle progression.
Three nitrosourea analogs, 1,3-bis(2-chloroethyl)-1-nitrosourea, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea, and 1-trans-(2… 
Highly Cited
1975
Highly Cited
1975
Carbamoylation of amino acid, peptides, and proteins by nitrosoureas.
Incubation at approximately physiological conditions of amino acids, peptides, and proteins with 1-(2-chloroethyl)-3-cyclohexyl-1… 
Highly Cited
1970
Highly Cited
1970
THE FIXATION OF COMPLEMENT AND THE ACTIVATED FIRST COMPONENT (C1) OF COMPLEMENT BY COMPLEXES FORMED BETWEEN ANTIBODY AND DIVALENT HAPTEN
Hapten-antibody complexes prepared at equivalence with the bivalent hapten bis-DNP-octamethylene-diamine and purified rabbit anti… 
Highly Cited
1967
Highly Cited
1967
Alkylating activity of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds.
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