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Nitrosourea Compounds

Known as: nitrosureas, Nitrosourea Compound, nitrosurea 
Any of a class of alkylating agents that contain both a nitroso group and a urea. They are lipophilic and can cross the blood-brain barrier.
National Institutes of Health

Papers overview

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Review
1998
Review
1998
The mouse will play a pivotal role in mammalian gene function studies as we enter the post-genomics era. The challenge is to… 
Highly Cited
1996
Highly Cited
1996
To dissect the multigenic control of colon tumour susceptibility in the mouse1 we used the set of 20 CcS/Dem (CcS) recombinant… 
Review
1987
Review
1987
Neurogenic tumors were selectively induced in high incidence in F344 rats by a single transplacental exposure to the direct… 
Highly Cited
1980
Highly Cited
1980
Inhibitors of poly(ADP-ribose) polymerase show a synergistic potentiation of cytotoxicity with certain DNA-damaging agents. Non… 
Highly Cited
1977
Highly Cited
1977
The lack of effective chemotherapy in advanced colon cancer and difficulties in evaluating response in clinical trials indicate a… 
Review
1975
Review
1975
The nitrosourea group of antitumor agents was developed by the Division of Cancer Treatment of the National Cancer Institute…