Nitrosourea Compounds

Known as: nitrosureas, Nitrosourea Compound, nitrosurea 
Any of a class of alkylating agents that contain both a nitroso group and a urea. They are lipophilic and can cross the blood-brain barrier.
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
By screening N-ethyl-N-nitrosourea-mutagenized animals for alterations in rhythms of wheel-running activity, we identified a… (More)
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Highly Cited
2006
Highly Cited
2006
BMS-354825 (dasatinib) and AMN107 (nilotinib) are potent alternate Abl inhibitors with activity against many imatinib mesylate… (More)
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Highly Cited
2003
Highly Cited
2003
In humans, ten Toll-like receptor (TLR) paralogues sense molecular components of microbes, initiating the production of cytokine… (More)
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Highly Cited
2002
Highly Cited
2002
The zebrafish has become a favorite organism for genetic analysis of vertebrate development, but methods for generating mutants… (More)
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Highly Cited
2001
Highly Cited
2001
The t(8;21) is one of the most frequent chromosomal abnormalities associated with acute myeloid leukemia (AML). The translocation… (More)
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Highly Cited
1997
Highly Cited
1997
Quantitative magnetic resonance imaging was performed to evaluate water diffusion and relaxation times, T1 and T2, as potential… (More)
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Highly Cited
1996
Highly Cited
1996
Systematic genome-wide mutagenesis screens for embryonic phenotypes have been instrumental in the understanding of invertebrate… (More)
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Highly Cited
1994
Highly Cited
1994
We studied the efficiency with which two chemical mutagens, ethyl methanesulfonate (EMS) and N-ethyl-N-nitrosourea (ENU) can… (More)
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Highly Cited
1990
Highly Cited
1990
In a prospective randomized trial designed to study the effectiveness of adjuvant chemotherapy following standard surgical… (More)
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Highly Cited
1980
Highly Cited
1980
Within three weeks of definitive surgical intervention, 467 patients with histologically proved malignant glioma were randomized… (More)
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