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Nitrosourea Compounds

Known as: nitrosureas, Nitrosourea Compound, nitrosurea 
Any of a class of alkylating agents that contain both a nitroso group and a urea. They are lipophilic and can cross the blood-brain barrier.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Intracellular lipopolysaccharide from Gram-negative bacteria including Escherichia coli, Salmonella typhimurium, Shigella… Expand
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Review
2006
Review
2006
Classical genetic methods, driven by phenotype rather than hypotheses, generally permit the identification of all proteins that… Expand
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Highly Cited
2006
Highly Cited
2006
Here we have identified 'triple D' (3d), a recessive N-ethyl-N-nitrosourea-induced mutation and phenotype in which no signaling… Expand
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Highly Cited
2005
Highly Cited
2005
Toll-like receptor 2 (TLR2) is required for the recognition of numerous molecular components of bacteria, fungi and protozoa. The… Expand
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Highly Cited
2005
Highly Cited
2005
The recessive mutation 'Heedless' (hdl) was detected in third-generation N-ethyl-N-nitrosourea–mutated mice that showed defective… Expand
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Highly Cited
2004
Highly Cited
2004
Several subsets of dendritic cells have been shown to produce type I IFN in response to viral infections, thereby assisting the… Expand
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Highly Cited
1997
Highly Cited
1997
Poly(ADP-ribose) polymerase [PARP; NAD+ ADP-ribosyltransferase; NAD+: poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D… Expand
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Highly Cited
1996
Highly Cited
1996
Systematic genome-wide mutagenesis screens for embryonic phenotypes have been instrumental in the understanding of invertebrate… Expand
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Highly Cited
1994
Highly Cited
1994
In a search for genes that regulate circadian rhythms in mammals, the progeny of mice treated with N-ethyl-N-nitrosourea (ENU… Expand
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Highly Cited
1980
Highly Cited
1980
Within three weeks of definitive surgical intervention, 467 patients with histologically proved malignant glioma were randomized… Expand
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