BIRC6 protein, human

Known as: Ubiquitin-Conjugating BIR Domain Enzyme Apollon, Apollon protein, human, BRUCE protein, human 
Baculoviral IAP repeat-containing protein 6 (4829 aa, ~528 kDa) is encoded by the human BIRC6 gene. This protein is involved in both the inhibition… (More)

Topic mentions per year

Topic mentions per year

1963-2018
051019632018

Papers overview

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2014
2014
Treatment resistance, the major challenge in the management of advanced prostate cancer, is in part based on resistance to… (More)
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2013
2013
INTRODUCTION Non-small-cell lung cancer (NSCLC) is an aggressive, highly chemoresistant disease. Reliable prognostic assays and… (More)
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2012
2012
The identification of intracellular signaling pathways that promote cell proliferation and resistance to cell death may lead to… (More)
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2007
2007
PURPOSE The genes that encode inhibitor of apoptosis proteins are frequently overexpressed in human cancers and can be associated… (More)
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Highly Cited
2005
Highly Cited
2005
Baculoviral inhibitor of apoptosis repeat-containing (Birc)6 gene/BIRC6 (Bruce/APOLLON) encodes an inhibitor of apoptosis and a… (More)
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2005
2005
Smac/DIABLO, HtrA2/Omi, and caspase-9 play key roles in the initiation of apoptosis. The inhibitor of apoptosis proteins (IAPs… (More)
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2005
2005
Apollon/BRUCE is a giant IAP protein that has BIR and UBC domains in its amino- and carboxy-terminals, respectively. Apollon… (More)
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Highly Cited
2004
Highly Cited
2004
Apollon (also known as BRUCE or BIRC6) is a large protein containing baculoviral-IAP-repeat (BIR) and ubiquitin-conjugating… (More)
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2000
2000
The human neuronal apoptosis inhibitory protein (NAIP) gene has been discovered as a candidate gene for spinal muscular atrophy… (More)
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Highly Cited
1999
Highly Cited
1999
IAP is a family of protein that has baculovirus IAP repeat (BIR) domains and inhibits apoptosis. We found a human IAP family gene… (More)
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