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Biological Insights From 108 Schizophrenia-Associated Genetic Loci
Associations at DRD2 and several genes involved in glutamatergic neurotransmission highlight molecules of known and potential therapeutic relevance to schizophrenia, and are consistent with leading pathophysiological hypotheses.
Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives.
Whole-brain anatomical networks: Does the choice of nodes matter?
Genome-wide association study identifies five new schizophrenia loci
The role of common genetic variation in schizophrenia in a genome-wide association study of substantial size is examined, suggesting MIR137-mediated dysregulation as a previously unknown etiologic mechanism in schizophrenia.
Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison
Theory of mind impairment in schizophrenia: Meta-analysis
Altered corticostriatal functional connectivity in obsessive-compulsive disorder.
- B. Harrison, C. Soriano-Mas, N. Cardoner
- Biology, PsychologyArchives of general psychiatry
- 1 November 2009
This study directly supports the hypothesis that OCD is associated with functional alterations of brain corticostriatal networks, as measured from coherent spontaneous fluctuations in the blood oxygenation level-dependent signal.
Gray matter abnormalities in Major Depressive Disorder: a meta-analysis of voxel based morphometry studies.
Executive function and attention deficit hyperactivity disorder: stimulant medication and better executive function performance in children
- S. Kempton, A. Vance, P. Maruff, E. Luk, J. Costin, C. Pantelis
- Psychology, MedicinePsychological Medicine
- 1 May 1999
Assessment of executive function in medicated and non-medicated children with ADHD using a computerized battery, the Cambridge Neuropsychological Test Automated Battery (CANTAB), which is sensitive to executive function deficits in older patients with frontostriatal neurological impairments found ADHD is associated with deficits in executive function.
Normative Data From the Cantab. I: Development of Executive Function Over the Lifespan
This paper addresses issues using the computer-based Cambridge Neuropsychological Test Automated Battery to identify periods of development in executive capacities using a normative sample of 194 participants ranging in age from 8 to 64 years, providing support for the vulnerability of executive skills to normal aging.