Leukotriene C4

Known as: Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))-, Leukotriene C 4, Leukotriene C4 [Chemical/Ingredient] 
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as… (More)
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
Adaptive immune responses begin after antigen-bearing dendritic cells (DCs) traffic from peripheral tissues to lymph nodes. Here… (More)
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Highly Cited
1999
Highly Cited
1999
The cysteinyl leukotrienes—leukotriene C4(LTC4), leukotriene D4(LTD4) and leukotriene E4(LTE 4)—are important mediators of human… (More)
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Highly Cited
1998
Highly Cited
1998
Aspirin causes bronchoconstriction in aspirin-intolerant asthma (AIA) patients by triggering cysteinyl-leukotriene (cys-LT… (More)
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Highly Cited
1996
Highly Cited
1996
The 190-kDa multidrug resistance protein (MRP) has recently been associated with the transport of cysteinyl leukotrienes and… (More)
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Review
1995
Review
1995
The glutathione S-transferases (GST) represent a major group of detoxification enzymes. All eukaryotic species possess multiple… (More)
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Highly Cited
1994
Highly Cited
1994
The multidrug resistance-associated protein (MRP) is the product of an ATP-binding cassette transporter gene overexpressed in… (More)
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Review
1987
Review
1987
Arachidonic acid is released from membrane phospholipids upon cell stimulation (for example, by immune complexes and calcium… (More)
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Highly Cited
1983
Highly Cited
1983
Arachidonic acid plays a central role in a biological control system where such oxygenated derivatives as prostaglandins… (More)
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Highly Cited
1983
Highly Cited
1983
5-Lipoxygenase pathway-derived products of arachidonic acid released by human eosinophils activated in vitro have been measured… (More)
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Highly Cited
1980
Highly Cited
1980
Slow reacting substance of anaphylaxis (SRS-A) is released by various stimuli, including immunological challenge, and has long… (More)
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