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Leukotriene C4

Known as: Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))-, Leukotriene C 4, Leukotriene C4 [Chemical/Ingredient] 
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as… 
National Institutes of Health

Related topics

Related topics

14 relations
In BloodLTC4S geneLeukotriene C1Process of secretion

Broader (2)

Leukotrienes CSRS-A

Narrower (1)

leukotriene C4 monomethyl ester

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Polymorphonuclear Leukocyte-Platelet Interaction: Role of P-Selectin in Thromboxane B2 and Leukotriene C4 Cooperative Synthesis
Summary In PMN/platelet suspensions stimulated by fMLP giant mixed aggregates are formed and TxB2 and LTC4 are synthesized as the… 
Highly Cited
1992
Highly Cited
1992
Urinary leukotriene E4 after exercise challenge in children with asthma.
Highly Cited
1988
Highly Cited
1988
Generation of leukotriene C4, leukotriene B4, and prostaglandin D2 by immunologically activated rat intestinal mucosa mast cells.
Mucosal mast cells (MMC) were isolated from the intestine of Nippostrongylus brasiliensis-infected rats and then activated with… 
Highly Cited
1987
Highly Cited
1987
Modulation of fibroblast proliferation by sulfidopeptide leukotrienes: effect of indomethacin.
Because infiltration of mononuclear cells and fibroblast proliferation are associated in chronic inflammatory lesions, we tested… 
Highly Cited
1987
Highly Cited
1987
Mouse bone marrow-derived mast cells cocultured with fibroblasts. Morphology and stimulation-induced release of histamine, leukotriene B4, leukotriene C4, and prostaglandin D2.
Mouse bone marrow-derived mast cells (BMMC), cultured for 2, 7, or 14 days in WEHI-3 conditioned medium in the absence or… 
Highly Cited
1985
Highly Cited
1985
Allergen‐Induced Release of Sulphidopeptide Leukotrienes (SRS‐A) and LTB4 in Allergic Rhinitis
Leukotrienes are a recently discovered group of arachidonic acid‐derived lipid mediators. Using radioimmunoassay and high… 
Highly Cited
1985
Highly Cited
1985
Leukotrienes B4, C4 and D4 stimulate DNA synthesis in cultured human epidermal keratinocytes
Leukotrienes in psoriatic skin lesions are potent mediators of inflammation. We have studied the capacity of leukotrienes to… 
Highly Cited
1982
Highly Cited
1982
IgE-dependent release of leukotriene C4 from alveolar macrophages
Slow reacting substances (SRS) are potent bronchoconstrictors that are thought to be important in the pathophysiology of asthma1… 
Highly Cited
1981
Highly Cited
1981
Tetraene and pentaene leukotrienes: selective production from murine mastocytoma cells after dietary manipulation.
Highly Cited
1980
Highly Cited
1980
Inhibition of leukotriene C and leukotriene D biosynthesis.
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