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SRS-A

Known as: SRS-A [Chemical/Ingredient], Slow Reacting Substance of Anaphylaxis 
A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions… 
National Institutes of Health

Related topics

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18 relations

Narrower (8)

2-norleukotriene D1Leukotriene C4Leukotriene D4leukotriene C-3
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

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Highly Cited
1985
Highly Cited
1985
Bronchial hyperreactivity to leucotriene D4 and histamine in exogenous asthma.
Reactivity of the small and large airways to inhaled leucotriene D4, one of the leucotrienes that constitute slow reacting… 
Highly Cited
1983
Highly Cited
1983
Conversion of leukotriene D4 to leukotriene E4 by a dipeptidase released from the specific granule of human polymorphonuclear leucocytes.
Leukotriene D4 (LTD4), the most active spasmogenic leukotriene constituent of the slow reacting substance of anaphylaxis was… 
Highly Cited
1982
Highly Cited
1982
Contractile activities of several cysteine-containing leukotrienes in the guinea-pig lung strip.
Highly Cited
1981
Highly Cited
1981
IDENTIFICATION OF LEUKOTRIENES D AND B IN SPUTUM FROM CYSTIC FIBROSIS PATIENTS
Highly Cited
1980
Highly Cited
1980
Preliminary studies of an acid-labile factor (ALF) in human sera that inactivates platelet-activating factor (PAF).
Highly Cited
1980
Highly Cited
1980
Leukotriene C elicits a prolonged excitation of cerebellar Purkinje neurons
Highly Cited
1973
Highly Cited
1973
Immunologic release of histamine and slow reacting substance of anaphylaxis from human lung. V. Effects of prostaglandins on release of histamine.
The capacity of prostaglandins to suppress the IgE-dependent antigen-induced release of histamine from human lung tissue requires… 
Highly Cited
1972
Highly Cited
1972
Release of histamine and slow reacting substance of anaphylaxis (SRS-A) by IgE-anti-IgE reactions on monkey mast cells.
Lung cell suspensions were obtained from Macaca irus passively sensitized with E myeloma protein and human IgG. By… 
Highly Cited
1971
Highly Cited
1971
Immunological release of histamine and slow reacting substance of anaphylaxis from human lung. II. Influence of cellular levels of cyclic AMP.
Highly Cited
1970
Highly Cited
1970
The capacity of human immunoglobulin E to mediate the release of histamine and slow reacting substance of anaphylaxis (SRS-A) from monkey lung.
Monkey lung fragments passively sensitized in vitro with human serum rich in IgE antibody released both histamine and slow… 
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