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SRS-A

Known as: SRS-A [Chemical/Ingredient], Slow Reacting Substance of Anaphylaxis 
A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions… 
National Institutes of Health

Related topics

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18 relations

Narrower (8)

2-norleukotriene D1Leukotriene C4Leukotriene D4leukotriene C-3
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

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1986
1986
Subcellular distribution of leukotriene C4 binding units in cultured bovine aortic endothelial cells.
The subcellular distribution of specific binding sites for [3H]leukotriene C4 ([3H]LTC4) was analyzed after sedimentation of… 
1983
1983
Comparison of cutaneous hyperemia in cattle elicited by larvae ofBoophilus microplus and by prostaglandins and other mediators
Blood flow has been measured in bovine skin following the injection of tick antigens and a number of pharmacological mediators… 
Highly Cited
1981
Highly Cited
1981
Radioimmunoassay of the leukotrienes of slow reacting substance of anaphylaxis.
A rabbit immunized with a conjugate of leukotriene D4 (LTD4) and bovine albumin via the icosanoid carboxyl produced antibodies… 
1979
1979
The immunological generation of a platelet-activating factor and a platet-lytic factor in the rat.
Antigen challenge of the rat peritoneal cavity which had been prepared with IgGa-rich antiserum generated activities which… 
Highly Cited
1978
Highly Cited
1978
Ionophore A 23187-induced production of slow reacting substance of anaphylaxis (SRS-A) by rat peritoneal cells in vitro: evidence for production by mononuclear cells.
A slow reacting substance is produced when mixed peritoneal cells from rats are incubated with low concentrations of the… 
1977
1977
Further studies on the SRS-A antagonist FPL 55712.
FPL 55712, previously reported to be a selective antagonist of SRS-A on the guinea-pig ileum, has now been shown to be similarly… 
1976
1976
Modulation of the release of SRS-A from bovine lung in vitro by several autonomic and autacoid agents.
The immunological release of slow-reacting substance of anaphylaxis (SRS-A) from bovine lung is modulated by several autonomic… 
1975
1975
Modulation of the formation and release of bovine SRS-A in vitro by several anti-anaphylactic drugs.
Slow-reacting substance of anaphylaxis (SRS-A) is released immunologically from bovine lung in vitro. Various drugs known to… 
1971
1971
Drug-induced modulation of the immunologic release of histamine and slow reacting substance of anaphylaxis.
Highly Cited
1964
Highly Cited
1964
BRONCHOCONSTRICTOR ACTION AND ANTAGONISM OF A SLOW-REACTING SUBSTANCE FROM ANAPHYLAXIS OF GUINEA-PIG ISOLATED LUNG.
Slow-reacting substance produced in anaphylaxis (SRS-A) increased resistance of the lungs to inflation in the guinea-pig in vivo…