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A Symbiotic View of Life: We Have Never Been Individuals
Recognizing the “holobiont”—the multicellular eukaryote plus its colonies of persistent symbionts—as a critically important unit of anatomy, development, physiology, immunology, and evolution opens up new investigative avenues and conceptually challenges the ways in which the biological subdisciplines have heretofore characterized living entities. Expand
Evidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses.
The results suggest that SP-D--alone, and in conjunction with SP-A and phagocytic cells--constitutes an important component of the natural immune response to IAV infection within the respiratory tract. Expand
Metchnikoff and the phagocytosis theory
  • A. Tauber
  • Biology, Medicine
  • Nature Reviews Molecular Cell Biology
  • 1 November 2003
Metchnikoff's phagocytosis theory was less an explanation of host defence than a proposal that might account for establishing and maintaining organismal 'harmony'. By tracing the phagocyte's variousExpand
An NADPH oxidase superoxide-generating system in the rabbit aorta.
The present studies were undertaken to characterize the source of superoxide in rabbit aorta and found that whole aortic tissue exhibited NADPH-dependent superoxide production that was inhibited by 1 microM diphenyleneiodonium. Expand
Contrasting actions of staurosporine, a protein kinase C inhibitor, on human neutrophils and primary mouse epidermal cells.
The effectiveness of staurosporine as a protein kinase C inhibitor in intact cells may depend markedly on the cell system, and, in keratinocytes, its activity is suggestive of a tumor promoter rather than of an inhibitor of tumor promotion. Expand
Seeking the foundations of cognition in bacteria: From Schrödinger's negative entropy to latent information
We reexamine Schrodinger's reflections on the fundamental requirements for life in view of new observations about bacterial self-organization and the emerging understanding of gene-network regulationExpand
Patient Autonomy And The Ethics Of Responsibility
The principle of patient autonomy dominates the contemporary debate over medical ethics. In this examination of the doctor-patient relationship, physician and philosopher Alfred Tauber argues thatExpand
Outside the subject
Identification of distinct activation pathways of the human neutrophil NADPH-oxidase.
The studies in toto suggest that OZ stimulation of the NADPH-oxidase differs from PMA, in that the particulate stimulus is PLA2 mediated and independent of protein kinase C. Expand