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Leukotriene D4

Known as: Leukotriene D-4, Leukotriene D 4, Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))- 
One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage… 
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Leukotrienes are metabolites of arachidonic acid derived from the action of 5-LO (5-lipoxygenase). The immediate product of 5-LO… 
Review
2001
Review
2001
  • Z. Kmieć
  • Advances in Anatomy Embryology and Cell Biology
  • 2001
  • Corpus ID: 7714118
The liver lobule is formed by parenchymal cells, i.e., hepatocytes and nonparenchymal cells. In contrast to hepatocytes that… 
Highly Cited
1999
Highly Cited
1999
The cysteinyl leukotrienes—leukotriene C4(LTC4), leukotriene D4(LTD4) and leukotriene E4(LTE 4)—are important mediators of human… 
Highly Cited
1995
Highly Cited
1995
The multidrug resistant cell lines HL60/AR and GLC4/ADR show high overexpression of the gene encoding the multidrug resistance… 
Review
1994
Review
1994
  • W. Henderson
  • Annals of Internal Medicine
  • 1994
  • Corpus ID: 34810055
Leukotrienes, together with prostaglandins, thromboxanes, and lipoxins, are the major constituents of a group of biologically… 
Highly Cited
1990
Highly Cited
1990
The hypothesis that neutrophils play an important role in the pathogenesis of gastric ulceration induced by nonsteroidal anti… 
Highly Cited
1984
Highly Cited
1984
The comparative actions of inhaled leukotriene C4 (LTC4), leukotriene D4 (LTD4), and histamine were studied in six normal… 
Highly Cited
1982
Highly Cited
1982
Allergic pulmonary reactions in vivo lead to airway constriction and mucous secretion, whereas in vitro lung anaphylaxis lead to… 
Highly Cited
1980
Highly Cited
1980
Slow reacting substance of anaphylaxis (SRS-A) is released by various stimuli, including immunological challenge, and has long…