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Leukotriene D4

Known as: Leukotriene D-4, Leukotriene D 4, Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))- 
One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Group 2 innate lymphoid cells (ILC2s) play critical roles in the induction of type 2 inflammation, response to parasite infection… Expand
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Review
2007
Review
2007
Leukotrienes are metabolites of arachidonic acid derived from the action of 5-LO (5-lipoxygenase). The immediate product of 5-LO… Expand
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Review
2001
Review
2001
  • Z. Kmiec
  • Advances in Anatomy Embryology and Cell Biology
  • 2001
  • Corpus ID: 7714118
The liver lobule is formed by parenchymal cells, i.e., hepatocytes and nonparenchymal cells. In contrast to hepatocytes that… Expand
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Highly Cited
1999
Highly Cited
1999
The cysteinyl leukotrienes—leukotriene C4(LTC4), leukotriene D4(LTD4) and leukotriene E4(LTE 4)—are important mediators of human… Expand
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Highly Cited
1995
Highly Cited
1995
The multidrug resistant cell lines HL60/AR and GLC4/ADR show high overexpression of the gene encoding the multidrug resistance… Expand
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Highly Cited
1994
Highly Cited
1994
The multidrug resistance-associated protein (MRP) is the product of an ATP-binding cassette transporter gene overexpressed in… Expand
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Highly Cited
1990
Highly Cited
1990
The hypothesis that neutrophils play an important role in the pathogenesis of gastric ulceration induced by nonsteroidal anti… Expand
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Highly Cited
1984
Highly Cited
1984
The comparative actions of inhaled leukotriene C4 (LTC4), leukotriene D4 (LTD4), and histamine were studied in six normal… Expand
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Highly Cited
1982
Highly Cited
1982
Allergic pulmonary reactions in vivo lead to airway constriction and mucous secretion, whereas in vitro lung anaphylaxis lead to… Expand
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Highly Cited
1980
Highly Cited
1980
Slow reacting substance of anaphylaxis (SRS-A) is released by various stimuli, including immunological challenge, and has long… Expand
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