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A comprehensive classification system for lipids11 The evaluation of this manuscript was handled by the former Editor-in-Chief Trudy Forte. Published, JLR Papers in Press, February 16, 2005. DOI…
A comprehensive classification of lipids with a common platform that is compatible with informatics requirements has been developed to deal with the massive amounts of data that will be generated by the lipid community. Expand
Electrospray mass spectrometry of phospholipids.
The current level of understanding of the mechanisms involved in the formation of various product ions following collisional activation of molecular ion species generated by electrospray ionization of the common glycerophospholipids is presented. Expand
LMSD: LIPID MAPS structure database
- M. Sud, E. Fahy, +8 authors S. Subramaniam
- Computer Science, Biology
- Nucleic Acids Res.
- 10 November 2006
The LIPID MAPS Structure Database (LMSD) is a relational database encompassing structures and annotations of biologically relevant lipids that provides the capability to perform a substructure search or exact match for the structure drawn by the user. Expand
Lipidomics reveals a remarkable diversity of lipids in human plasma1[S]
- O. Quehenberger, Aaron M. Armando, +21 authors E. Dennis
- Biology, Medicine
- Journal of Lipid Research
- 1 November 2010
The focus of the present study was to define the human plasma lipidome and to establish novel analytical methodologies to quantify the large spectrum of plasma lipids and to quantitatively assessed the levels of over 500 distinct molecular species distributed among the main lipid categories. Expand
A comprehensive classification system for lipids.
A structured vocabulary will facilitate the systematization of lipid biology and enable the cataloging of lipids and their properties in a way that is compatible with other macromolecular databases. Expand
Biosynthesis and metabolism of leukotrienes.
These metabolic transformations of the primary leukotrienes are critical for termination of their biological activity, and defects in expression of participating enzymes may be involved in specific genetic disease. Expand
Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses
Observations suggest that macrophage activation in atherosclerotic lesions results from extrinsic, proinflammatory signals generated within the artery wall that suppress homeostatic and anti-inflammatory functions of desmosterol. Expand
Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents.
- A. Patwardhan, A. Akopian, +5 authors K. Hargreaves
- Chemistry, Medicine
- The Journal of clinical investigation
- 3 May 2010
These findings suggest a mechanism for integrating the hyperalgesic and proinflammatory roles of TRPV1 and linoleic acid metabolites and may provide the foundation for investigating new classes of analgesic drugs. Expand
Oxidative stress in severe pulmonary hypertension.
- R. Bowers, C. Cool, +4 authors N. Voelkel
- American journal of respiratory and critical care…
- 15 March 2004
It is concluded that indeed the lungs from patients with severe PH are under oxidative stress and that chronic prostacyclin infusion has an antiinflammatory effect on the lung tissue. Expand
Sublimation as a method of matrix application for mass spectrometric imaging
- J. Hankin, R. Barkley, R. Murphy
- Chemistry, Medicine
- Journal of the American Society for Mass…
- 1 September 2007
MALDI matrix could be readily applied to tissue sections on glass slides and stainless steel MALDI plate inserts as long as good thermal contact was made with the condenser of the sublimation device and the method was reproducible and eliminated the potential for spreading of analytes arising from solvent deposition during matrix application. Expand