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Lamivudine / Zidovudine

Known as: lamivudine, zidovudine drug combination, lamivudine zidovudine, lamivudine+zidovudine 
A combination of two synthetic nucleoside analogues with synergistic antiviral properties. Lamivudine is phosphorylated intracellularly to its active… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (4)

Anti-HIV AgentsDrug CombinationsReverse Transcriptase InhibitorsZidovudine

Narrower (1)

Combivir
Lamivudine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection.
BACKGROUND Antiretroviral drugs reduce viral replication and can reduce mother-to-child transmission of HIV either by lowering… 
Highly Cited
2010
Highly Cited
2010
Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection.
BACKGROUND The MERIT (Maraviroc versus Efavirenz in Treatment-Naive Patients) study compared maraviroc and efavirenz, both with… 
Highly Cited
2010
Highly Cited
2010
Antiretroviral treatment for children with peripartum nevirapine exposure.
BACKGROUND Single-dose nevirapine is the cornerstone of the regimen for prevention of mother-to-child transmission of human… 
Highly Cited
2007
Highly Cited
2007
Evolution of Antiretroviral Drug Costs in Brazil in the Context of Free and Universal Access to AIDS Treatment
Background Little is known about the long-term drug costs associated with treating AIDS in developing countries. Brazil's AIDS… 
Highly Cited
2003
Highly Cited
2003
Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection.
BACKGROUND The optimal sequencing of antiretroviral regimens for the treatment of infection with human immunodeficiency virus… 
Highly Cited
2003
Highly Cited
2003
Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection.
BACKGROUND It is unclear whether therapy for human immunodeficiency virus type 1 (HIV-1) should be initiated with a four-drug or… 
Highly Cited
1998
Highly Cited
1998
Maintenance antiretroviral therapies in HIV-infected subjects with undetectable plasma HIV RNA after triple-drug therapy. AIDS Clinical Trials Group Study 343 Team.
BACKGROUND Combination antiretroviral therapy with indinavir, zidovudine, and lamivudine can suppress the level of human… 
Highly Cited
1998
Highly Cited
1998
Mutations in hepatitis B DNA polymerase associated with resistance to lamivudine do not confer resistance to adefovir in vitro
To determine whether adefovir is active against lamivudine‐resistant hepatitis B virus (HBV), the inhibition constants of… 
Highly Cited
1998
Highly Cited
1998
A randomized trial of three maintenance regimens given after three months of induction therapy with zidovudine, lamivudine, and indinavir in previously untreated HIV-1-infected patients. Trilège…
BACKGROUND The long-term effectiveness of potent three-drug antiretroviral regimens for the treatment of human immunodeficiency… 
Highly Cited
1997
Highly Cited
1997
Human immunodeficiency virus drug therapy and virus load
Analysis of the short-term dynamics of human immunodeficiency virus (HIV) type 1 infection in response to drug therapy has… 
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