Lamivudine / Zidovudine

Known as: lamivudine, zidovudine drug combination, lamivudine zidovudine, lamivudine+zidovudine 
A combination of two synthetic nucleoside analogues with synergistic antiviral properties. Lamivudine is phosphorylated intracellularly to its active… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
05101519952017

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Single-dose nevirapine is the cornerstone of the regimen for prevention of mother-to-child transmission of human… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Durable suppression of replication of the human immunodeficiency virus (HIV) depends on the use of potent, well… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Atazanavir, an azapeptide protease inhibitor (PI), has pharmacokinetics that allow once-daily dosing, and it is not… (More)
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Highly Cited
2003
Highly Cited
2003
To determine the efficacy and safety of 2 inexpensive and easily deliverable antiretroviral (ARV) regimens for the prevention of… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND The optimal sequencing of antiretroviral regimens for the treatment of infection with human immunodeficiency virus… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND It is unclear whether therapy for human immunodeficiency virus type 1 (HIV-1) should be initiated with a four-drug or… (More)
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2003
2003
OBJECTIVES Nucleoside analog reverse transcriptase inhibitors (NRTI) are used in virtually all anti-HIV regimens. Clinical… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Efavirenz is a nonnucleoside reverse-transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). We… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Zidovudine is commonly administered during pregnancy to prevent mother-to-child HIV-1 transmission. We investigated… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The efficacy and safety of adding a protease inhibitor to two nucleoside analogues to treat human immunodeficiency… (More)
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