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- Publications
- Influence
A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors
- A. Carr, K. Samaras, +4 authors D. Cooper
- Medicine
- AIDS
- 7 May 1998
Objective:To describe a syndrome of peripheral lipodystrophy (fat wasting of the face, limbs and upper trunk), hyperlipidaemia and insulin resistance in patients receiving potent HIV protease… Expand
Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: acohort study
- A. Carr, K. Samaras, A. Thorisdottir, G. Kaufmann, D. Cooper
- Medicine
- The Lancet
- 19 June 1999
BACKGROUND
The prevalence and severity of lipodystrophy syndrome with long-term therapy for HIV-1 infection that includes a protease inhibitor is unknown. We studied the natural course of the… Expand
Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection.
- J. Lundgren, A. Babiker, +16 authors J. Neaton
- Medicine
- The New England journal of medicine
- 27 August 2015
BACKGROUND
Data from randomized trials are lacking on the benefits and risks of initiating antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) infection who have a… Expand
Antiretroviral therapy in adults: updated recommendations of the International AIDS Society-USA Panel.
- C. Carpenter, D. Cooper, +15 authors P. Volberding
- Medicine
- JAMA
- 19 January 2000
OBJECTIVE
To update recommendations for antiretroviral therapy for adult human immunodeficiency virus type 1 (HIV-1) infection, based on new information and drugs that are available.
PARTICIPANTS
A… Expand
Adverse effects of antiretroviral therapy
Antiretroviral toxicity is an increasingly important issue in the management of HIV-infected patients. With the sustained major declines in opportunistic complications, HIV infection is a more… Expand
Antiretroviral treatment for adult HIV infection in 2002: updated recommendations of the International AIDS Society-USA Panel.
- P. Yeni, S. Hammer, +15 authors P. Volberding
- Medicine
- JAMA
- 10 July 2002
OBJECTIVE
New information warrants updated recommendations for the 4 central issues in antiretroviral therapy: when to start, what drugs to start with, when to change, and what to change to. These… Expand
Characterization of CD4+ CTLs Ex Vivo1
- V. Appay, J. Zaunders, +10 authors A. Kelleher
- Biology, Medicine
- The Journal of Immunology
- 1 June 2002
The cytotoxic potential of CD8+ T cells and NK cells plays a crucial role in the immune response to pathogens. Although in vitro studies have reported that CD4+ T cells are also able to mediate… Expand
Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials
- B. Clotet, N. Bellos, J. Molina, D. Cooper, O. B. O. T. P. 1. A. 2. S. groups
- Medicine
- The Lancet
- 7 April 2007
BACKGROUND
The continuing, randomised, multinational, phase IIB POWER 1 and 2 studies aim to evaluate efficacy and safety of darunavir in combination with low-dose ritonavir in treatment-experienced… Expand
Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection.
- D. Cooper, R. Steigbigel, +26 authors B. Nguyen
- Medicine
- The New England journal of medicine
- 24 July 2008
BACKGROUND
We evaluated the efficacy of raltegravir and the development of viral resistance in two identical trials involving patients who were infected with human immunodeficiency virus type 1… Expand
The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation
- F. Pereyra, Xiaoming Jia, +334 authors M. Zhao
- Biology, Medicine
- Science
- 10 December 2010
Getting HIV Under Control Approximately 1 in 300 people infected with HIV are HIV “controllers” who are able to maintain long-term control of the virus without medication and who do not progress to… Expand
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