Lamellipodia

Known as: Lamellipodias, lamellipodium 
A sheet-like cellular projection that is supported by an ordered network of actin microfilaments. This structure is involved in cellular motility and… (More)

Topic mentions per year

Topic mentions per year

1973-2017
05010015019732017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Cell migration is initiated by lamellipodia-membrane-enclosed sheets of cytoplasm containing densely packed actin filament… (More)
  • figure 1
  • figure 2
  • table I
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The Rho-GTPase Rac1 stimulates actin remodelling at the cell periphery by relaying signals to Scar/WAVE proteins leading to… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Lamellipodia are thin, veil-like extensions at the edge of cells that contain a dynamic array of actin filaments. We describe an… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Directed cell migration is critical for tissue morphogenesis and wound healing, but the mechanism of directional control is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Cadherin-dependent epithelial cell-cell adhesion is thought to be regulated by Rho family small GTPases and PI 3-kinase, but the… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Cortactin is an actin-binding protein that is enriched within the lamellipodia of motile cells and in neuronal growth cones. Here… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The leading edge (approximately 1 microgram) of lamellipodia in Xenopus laevis keratocytes and fibroblasts was shown to have an… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
he continuous remodelling of the actin cytoskeleton is a prerequisite for many cells to move and alter their shape. These… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Rho and rac, two members of the ras-related superfamily of small GTPases, regulate the polymerization of actin to produce stress… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
The organization and polarity of actin filaments in neuronal growth cones was studied with negative stain and freeze-etch EM… (More)
Is this relevant?