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Lamellipodia

Known as: Lamellipodias, lamellipodium 
A sheet-like cellular projection that is supported by an ordered network of actin microfilaments. This structure is involved in cellular motility and… 
National Institutes of Health

Related topics

Related topics

9 relations
AMOT protein, humanITSN1 protein, humanMicrofilamentsPodoplanin

Broader (1)

cell leading edge

Narrower (1)

growth cone lamellipodium

Papers overview

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Highly Cited
2012
Highly Cited
2012
A novel adipocytokine, vaspin inhibits platelet-derived growth factor-BB-induced migration of vascular smooth muscle cells.
Highly Cited
2005
Highly Cited
2005
Collapsin response mediator protein-4 regulates F-actin bundling.
Highly Cited
2002
Highly Cited
2002
Use of fluorescently labelled deoxyribonuclease I to spatially measure G-actin levels in migrating and non-migrating cells.
Lamellipodium protrusion is linked to actin filament disassembly in migrating fibroblasts [Cramer, 1999: Curr. Biol. 9:1095-1105… 
Highly Cited
2001
Highly Cited
2001
Delta regulates keratinocyte spreading and motility independently of differentiation
Highly Cited
2000
Highly Cited
2000
Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac
Frabin is an actin filament-binding protein which shows GDP/GTP exchange activity specific for Cdc42 small G protein and induces… 
Highly Cited
1989
Highly Cited
1989
Forward transport of glycoproteins on leading lamellipodia in locomoting cells
IN several types of locomoting cells, active rearward transport of particles on the cell surface has been observed and correlated… 
Highly Cited
1988
Highly Cited
1988
Centripetal transport of cytoplasm, actin, and the cell surface in lamellipodia of fibroblasts.
Wound healing in Swiss 3T3 cultures was investigated with video-enhanced contrast (VEC) microscopy. The formation of protrusions… 
Highly Cited
1982
Highly Cited
1982
Membrane activity and topography of F-Met-Leu-Phe-Treated polymorphonuclear leukocytes. Acute and sustained responses to chemotactic peptide.
The chemotactic peptide N-formylmethionyl-leucyl-phenylalanine (f-Met-Leu-Phe) causes a dramatic stimulation of membrane ruffling… 
Highly Cited
1981
Highly Cited
1981
The organization of actin in spreading macrophages. The actin-cytoskeleton of peritoneal macrophages is linked to the substratum via transmembrane connections.
Highly Cited
1981
Highly Cited
1981
Locomotion of Xenopus epidermis cells in primary culture.
The locomotion of single epidermis cells, grown out from Xenopus laevis tadpole tails has been investigated by time-lapse… 
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