Podoplanin

Known as: hT1alpha-2, Gp36, PA2.26 Antigen 
Podoplanin (162 aa, ~17 kDa) is encoded by the human PDPN gene. This protein plays a role in the determination of cell shape.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2017
020406019902017

Papers overview

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Highly Cited
2008
Highly Cited
2008
Recent studies have reported increased podoplanin expression by cancer cells and stromal cells, but little is known about its… (More)
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2008
2008
We have recently shown that the C-type lectin-like receptor, CLEC-2, is expressed on platelets and that it mediates powerful… (More)
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Highly Cited
2007
Highly Cited
2007
Podoplanin (aggrus), a transmembrane sialoglycoprotein, is involved in tumor cell-induced platelet aggregation, tumor metastasis… (More)
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Highly Cited
2007
Highly Cited
2007
Tumor cell-induced platelet aggregation has been reported to facilitate hematogenous metastasis. Aggrus/podoplanin is a platelet… (More)
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Highly Cited
2006
Highly Cited
2006
Podoplanin is a small membrane mucin expressed in tumors associated with malignant progression. It is enriched at cell-surface… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Podoplanin is a mucin-like glycoprotein that is important in lymphangiogenesis but not blood vessel formation. Recent… (More)
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Highly Cited
2006
Highly Cited
2006
Podoplanin (aggrus) is a mucin-like transmembrane sialoglycoprotein that is expressed on lymphatic endothelial cells. Podoplanin… (More)
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Highly Cited
2005
Highly Cited
2005
The mucin-type glycoprotein podoplanin is specifically expressed by lymphatic but not blood vascular endothelial cells in culture… (More)
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Highly Cited
2005
Highly Cited
2005
Podoplanin is a specific marker for lymph vessel endothelial cells. It was noted that podoplanin is expressed in reactive… (More)
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Highly Cited
1999
Highly Cited
1999
Angiosarcomas apparently derive from blood vessel endothelial cells; however, occasionally their histological features suggest… (More)
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