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Live imaging of the actin cytoskeleton is crucial for the study of many fundamental biological processes, but current approaches… Expand The actin cytoskeleton is a complex structure that performs a wide range of cellular functions. In 2001, significant advances… Expand Motile cells extend a leading edge by assembling a branched network of actin filaments that produces physical force as the… Expand The actin cytoskeleton mediates a variety of essential biological functions in all eukaryotic cells. In addition to providing a… Expand Focal adhesions are sites of tight adhesion to the underlying extracellular matrix developed by cells in culture. They provided a… Expand A new in vitro assay using a feedback enhanced laser trap system allows direct measurement of force and displacement that results… Expand The function of rac, a ras-related GTP-binding protein, was investigated in fibroblasts by microinjection. In confluent serum… Expand The dynamic behaviour of actin filaments has been directly observed in living, motile cells using fluorescence photoactivation… Expand C YTOCHALASINS and phalloidins are two groups of small, naturally occurring organic molecules that bind to actin and alter its… Expand In our opinion, all of the phenomena that are inhibited by cytochalasin can be thought of as resulting from contractile activity… Expand