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ITSN1 protein, human
Known as:
intersectin 1 (SH3 domain protein), human
, ITSN1
, Intersectin-1
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Intersectin-1 (1721 aa, ~195 kDa) is encoded by the human ITSN1 gene. This protein plays a role in the regulation of both small GTPase activity and…
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National Institutes of Health
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Related topics
Related topics
15 relations
Adaptor Signaling Protein Gene
C2 Domains
Calcium Binding
Calcium-Binding Proteins
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Silencing Intersectin 1 Slows Orthotopic Neuroblastoma Growth in Mice
Jamie C Harris
,
Erika Herrero-García
,
A. Russo
,
A. Kajdacsy-Balla
,
J. O’Bryan
,
B. Chiu
Journal of pediatric hematology/oncology
2017
Corpus ID: 8785308
Neuroblastoma accounts for 15% of all pediatric cancer deaths. Intersectin 1 (ITSN1), a scaffold protein involved in…
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2015
2015
Phosphatidylinositol 3-kinase, class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesis.
A. Russo
,
M. Okur
,
M. Bosland
,
J. O’Bryan
Cancer Letters
2015
Corpus ID: 34519201
2014
2014
Bioinformatics analysis of biomarkers and transcriptional factor motifs in Down syndrome
X. Kong
,
N. Liu
,
X. J. Xu
Brazilian journal of medical and biological…
2014
Corpus ID: 15139013
In this study, biomarkers and transcriptional factor motifs were identified in order to investigate the etiology and phenotypic…
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2013
2013
The LMP2A protein of Epstein-Barr virus regulates phosphorylation of ITSN1 and Shb adaptors by tyrosine kinases.
Oleksandr Dergai
,
M. Dergai
,
+4 authors
A. Rynditch
Cellular Signalling
2013
Corpus ID: 11184427
2013
2013
Receptor Tyrosine Kinase Ubiquitylation Involves the Dynamic Regulation of Cbl-Spry2 by Intersectin 1 and the Shp2 Tyrosine Phosphatase
M. Okur
,
A. Russo
,
J. O’Bryan
Molecular and Cellular Biology
2013
Corpus ID: 19824629
ABSTRACT Ubiquitylation of receptor tyrosine kinases (RTKs) regulates their trafficking and lysosomal degradation. The…
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2013
2013
Intersectin-1 L nucleotide exchange factor regulates secretory granule exocytosis by activating Cdc 42
Magali Malacombe
,
M. Ceridono
,
+4 authors
S. Gasman
2013
Corpus ID: 33205857
Magali Malacombe, Mara Ceridono, Valérie Calco, Sylvette Chasserot-Golaz, Peter S McPherson, Marie-France Bader and Stéphane…
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2012
2012
A New Dimension to Ras Function: A Novel Role for Nucleotide-Free Ras in Class II Phosphatidylinositol 3-Kinase Beta (PI3KC2β) Regulation
K. Wong
,
A. Russo
,
Xuerong Wang
,
Yun-Ju Chen
,
A. Lavie
,
J. O’Bryan
PLoS ONE
2012
Corpus ID: 14735067
The intersectin 1 (ITSN1) scaffold stimulates Ras activation on endocytic vesicles without activating classic Ras effectors. The…
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2012
2012
Endocytic adaptor protein intersectin 1 forms a complex with microtubule stabilizer STOP in neurons.
D. Morderer
,
O. Nikolaienko
,
+4 authors
A. Rynditch
Gene
2012
Corpus ID: 32014074
2011
2011
Identification and characterization of a novel mammalian isoform of the endocytic adaptor ITSN1.
M. Dergai
,
I. Skrypkina
,
+5 authors
A. Rynditch
Gene
2011
Corpus ID: 3660342
2011
2011
Wsp1, a GBD/CRIB Domain-Containing WASP Homolog, Is Required for Growth, Morphogenesis, and Virulence of Cryptococcus neoformans
G. Shen
,
A. Whittington
,
Ping Wang
Eukaryotic Cell
2011
Corpus ID: 9706335
ABSTRACT Human endocytic protein ITSN1 regulates actin reorganization by activating Rho family GTPases, such as Cdc42. The…
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