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ITSN1 protein, human

Known as: intersectin 1 (SH3 domain protein), human, ITSN1, Intersectin-1 
Intersectin-1 (1721 aa, ~195 kDa) is encoded by the human ITSN1 gene. This protein plays a role in the regulation of both small GTPase activity and… Expand
National Institutes of Health

Papers overview

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2015
2015
Phosphatidylinositol 3-kinases (PI3Ks) play important roles in human tumorigenesis. Activation of the PI3K target AKT is frequent… Expand
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2014
2014
Ubiquitylation of receptor tyrosine kinases (RTKs) regulates their trafficking and lysosomal degradation. The multidomain… Expand
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2014
2014
ABSTRACT Vaccinia virus enhances its cell-to-cell spread by inducing Arp2/3-dependent actin polymerisation. This process is… Expand
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2013
2013
Latent Membrane Protein 2A (LMP2A) is an Epstein-Barr virus-encoded protein that is important for the maintenance of latent… Expand
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2012
2012
Intersectin 1 (ITSN1) is a multidomain adaptor protein that functions in clathrin-mediated endocytosis and signal transduction… Expand
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2012
2012
Ubiquitylation of receptor tyrosine kinases plays a critical role in regulating the trafficking and lysosomal degradation of… Expand
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Highly Cited
2008
Highly Cited
2008
Enlarged early endosomes in the neurons of young Down syndrome (DS) and pre-Alzheimer's disease (AD) brains suggest that a… Expand
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Highly Cited
2006
Highly Cited
2006
Granzyme B is critical to the ability of natural killer cells and cytotoxic T lymphocytes to induce efficient cell death of… Expand
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2006
2006
Purpose: Humans with small deletions of chromosome 21 provide important models for understanding the role of dosage-sensitive… Expand
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Highly Cited
2000
Highly Cited
2000
Intersectin 1 (ITSN1) is a binding partner of dynamin that has been shown to participate in clathrin-mediated endocytosis. Here… Expand
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