ITSN1 protein, human

Known as: intersectin 1 (SH3 domain protein), human, ITSN1, Intersectin-1 
Intersectin-1 (1721 aa, ~195 kDa) is encoded by the human ITSN1 gene. This protein plays a role in the regulation of both small GTPase activity and… (More)

Topic mentions per year

Topic mentions per year

2000-2018
024620002018

Papers overview

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2015
2015
Phosphatidylinositol 3-kinases (PI3Ks) play important roles in human tumorigenesis. Activation of the PI3K target AKT is frequent… (More)
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2013
2013
Latent Membrane Protein 2A (LMP2A) is an Epstein-Barr virus-encoded protein that is important for the maintenance of latent… (More)
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2012
2012
Ubiquitylation of receptor tyrosine kinases plays a critical role in regulating the trafficking and lysosomal degradation of… (More)
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2012
2012
Members of the intersectin (ITSN) family of scaffold proteins consist of multiple modular domains, each with distinct ligand… (More)
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2010
2010
SH3 domains function as protein-protein interaction modules in assembly of signalling and endocytic protein complexes. Here we… (More)
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2009
2009
Intersectin 1 (ITSN1) is an adaptor protein involved in clathrin-mediated endocytosis, apoptosis, signal transduction and… (More)
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2008
2008
Enlarged early endosomes in the neurons of young Down syndrome (DS) and pre-Alzheimer's disease (AD) brains suggest that a… (More)
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2008
2008
Intersectin 1 (ITSN1) is a conserved adaptor protein implicated in endocytosis, regulation of actin cytoskeleton rearrangements… (More)
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2008
2008
We identified intersectin1 (ITSN1) as a new binding partner of the SH2 domain containing inositol 5-phosphatase 2 (SHIP2). The… (More)
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2000
2000
Intersectin 1 (ITSN1) is a binding partner of dynamin that has been shown to participate in clathrin-mediated endocytosis. Here… (More)
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