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C2 Domains

Known as: C2 Domain, Domain, C2, Domains, C2 
Some isozymes of protein kinase C (PKC) contain a domain, known as C2, of about 116 amino-acid residues which is located between the two copies of… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
C2 domains are membrane-binding modules that share a common overall fold: a single compact Greek-key motif organized as an eight… Expand
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Highly Cited
2010
Highly Cited
2010
Eukaryotes contain an elaborate membrane system, which bounds the cell itself, nuclei, organelles and transient intracellular… Expand
Review
2006
Review
2006
C2 domains are a ubiquitous structural module and many of them function in Ca2+ -dependent membrane binding and thereby serve as… Expand
Highly Cited
2006
Highly Cited
2006
Background: The molecular basis of autosomal recessive non-syndromic mental retardation (NSMR) is poorly understood, mostly owing… Expand
Highly Cited
2005
Highly Cited
2005
Summary In eukaryotic cells, the SH2 and PTB domains mediate protein-protein interactions by recognizing phosphotyrosine residues… Expand
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Highly Cited
2002
Highly Cited
2002
Many proteins involved in signal transduction and vesicle trafficking contain C2 domains whose membrane association is often… Expand
Highly Cited
1998
Highly Cited
1998
In an attempt to identify proteins that might underlie membrane trafficking processes in ciliates, calcium-dependent… Expand
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Review
1996
Review
1996
The C2 domain is a Ca2+‐binding motif of approximately 130 residues in length originally identified in the Ca2+‐dependent… Expand
Highly Cited
1996
Highly Cited
1996
C2 domains are found in many proteins involved in membrane traffic or signal transduction. Although C2 domains are thought to… Expand
Highly Cited
1993
Highly Cited
1993
Synaptotagmin I is a Ca(2+)- and phospholipid-binding protein of synaptic vesicles with an essential function in… Expand