C2 Domains

Known as: C2 Domain, Domain, C2, Domains, C2 
Some isozymes of protein kinase C (PKC) contain a domain, known as C2, of about 116 amino-acid residues which is located between the two copies of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Phospholipid-binding modules such as PH, C1, and C2 domains play crucial roles in location-dependent regulation of many protein… (More)
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2009
2009
Neurotransmitter release is triggered by cooperative Ca2+-binding to the Ca2+-sensor protein synaptotagmin-1. Synaptotagmin-1… (More)
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Highly Cited
2006
Highly Cited
2006
Synaptotagmin I is a synaptic vesicle associated membrane protein that appears to regulate Ca(2+)-mediated exocytosis. Here, the… (More)
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2004
2004
Translocation of cytosolic phospholipase A2 (cPLA2) to Golgi and ER in response to intracellular calcium mobilization is… (More)
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Highly Cited
2003
Highly Cited
2003
Synaptotagmin is a synaptic vesicle protein that has been proposed to be the calcium sensor responsible for fast neurotransmitter… (More)
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2002
2002
The C2 domain is a Ca(2+)-dependent membrane-targeting module found in many cellular proteins involved in signal transduction or… (More)
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2001
2001
The ubiquitous C2 domain is a conserved Ca2+ triggered membrane-docking module that targets numerous signaling proteins to… (More)
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1999
1999
The C2 domain acts as a membrane-targeting module in a diverse group of proteins including classical protein kinase Cs (PKCs… (More)
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1999
1999
Synaptotagmins (Syts) are a family of vesicle proteins that have been implicated in both regulated neurosecretion and general… (More)
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1994
1994
Synaptotagmin, an integral membrane protein localized to secretory vesicles, has been implicated in the docking and fusion steps… (More)
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