LY 354740

Known as: LY-354740, LY354740 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
LY354740, a potent and selective mGlu (metabotropic glutamate receptor)2/3 agonist, has shown efficacy in the treatment of… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE To assess the neuroprotective effects of different glutamate modulation strategies, with a nonselective (MK801) and a… (More)
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Review
2003
Review
2003
Lilly is developing LY-354740, the lead compound in a series of derivatives of the metabotropic glutamate receptor group II… (More)
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Highly Cited
2003
Highly Cited
2003
LY354740, a structural analogue of glutamate that shows specificity at the mGluR2/3 receptor, has anxiolytic effects in animal… (More)
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Highly Cited
2000
Highly Cited
2000
In prefrontal cortex, 5-hydroxytryptamine(2A) (5-HT(2A)) receptors have been linked to the action of hallucinogens and atypical… (More)
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Highly Cited
2000
Highly Cited
2000
Recent electrophysiological studies in our laboratory have demonstrated a physiological interaction between 5-HT2A and… (More)
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1999
1999
Despite there being a lot of biochemical data about metabotropic glutamate (mGlu) receptors, our knowledge of the behavioural… (More)
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Highly Cited
1999
Highly Cited
1999
As part of our ongoing research program aimed at the identification of highly potent, selective, and systemically active agonists… (More)
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Highly Cited
1997
Highly Cited
1997
In vivo microdialysis in freely moving rats was used to investigate the presynaptic mechanisms by which LY354740, a novel, potent… (More)
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Highly Cited
1997
Highly Cited
1997
The novel compound LY354740 is a conformationally constrained analog of glutamate, which was designed for interaction at… (More)
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