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LY 354740

Known as: LY-354740, LY354740 
National Institutes of Health

Papers overview

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Review
2011
Review
2011
In vitro models of traumatic brain injury (TBI) are helping elucidate the pathobiological mechanisms responsible for dysfunction… Expand
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Highly Cited
2003
Highly Cited
2003
Previous studies have shown that the metabotropic glutamate receptor (mGluR)2/3 agonist LY354740 attenuated glutamate release in… Expand
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Highly Cited
2003
Highly Cited
2003
RationaleLY354740, a structural analogue of glutamate that shows specificity at the mGluR2/3 receptor, has anxiolytic effects in… Expand
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Review
2001
Review
2001
Metabotropic glutamate (mGlu) receptors have been considered as potential targets for neuroprotective drugs, but the lack of… Expand
Highly Cited
2000
Highly Cited
2000
In prefrontal cortex, 5-hydroxytryptamine(2A) (5-HT(2A)) receptors have been linked to the action of hallucinogens and atypical… Expand
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Highly Cited
1999
Highly Cited
1999
Previous animal studies have indicated that drugs targeted at metabotropic glutamate (mGlu) receptors may be useful for treatment… Expand
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Highly Cited
1999
Highly Cited
1999
As part of our ongoing research program aimed at the identification of highly potent, selective, and systemically active agonists… Expand
Highly Cited
1998
Highly Cited
1998
LY354740 is a conformationally constrained analog of glutamate which is a potent agonist for group II cAMP coupled metabotropic… Expand
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Highly Cited
1997
Highly Cited
1997
2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (9) was designed as a conformationally constrained analog of glutamic acid. For… Expand
Highly Cited
1997
Highly Cited
1997
The novel compound LY354740 is a conformationally constrained analog of glutamate, which was designed for interaction at… Expand