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KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 1

Known as: GAP-Associated Tyrosine Phosphoprotein p62, p21 Ras GTPase-Activating Protein-Associated p62, Sam68 
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (443 aa, ~48 kDa) is encoded by the human KHDRBS1 gene. This protein is… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is a neurodegenerative disorder caused by expansion of 55-200 CGG repeats in… Expand
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Highly Cited
2010
Highly Cited
2010
Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by loss of motor neurons in patients with null mutations in… Expand
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Highly Cited
2007
Highly Cited
2007
Enzymes that mediate reversible epigenetic modifications have not only been recognized as key in regulating gene expression and… Expand
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Highly Cited
2003
Highly Cited
2003
Dimethylation at arginine residues has been shown to be central in cellular processes such as signal transduction, transcription… Expand
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Highly Cited
2003
Highly Cited
2003
RNA binding proteins often contain multiple arginine glycine repeats, a sequence that is frequently methylated by protein… Expand
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Highly Cited
2002
Highly Cited
2002
Evolution of human organismal complexity from a relatively small number of genes—only approximately twice that of worm or fly—is… Expand
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Highly Cited
2001
Highly Cited
2001
Leptin, the adipocyte-secreted hormone that centrally regulates weight control, is known to function as an immunomodulatory… Expand
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Highly Cited
2000
Highly Cited
2000
Sik (mouse Src-related intestinal kinase) and its orthologue BRK (human breast tumor kinase) are intracellular tyrosine kinases… Expand
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Highly Cited
2000
Highly Cited
2000
Src homology 3 (SH3) and WW domains are known to associate with proline-rich motifs within their respective ligands. Here we… Expand
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Highly Cited
1997
Highly Cited
1997
Sam68, a specific target of the Src tyrosine kinase in mitosis, possesses features common to RNA-binding proteins, including a K… Expand
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