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Adaptor Proteins, Signal Transducing

Known as: Adapter Signaling Protein, Signal Transducing Adaptor Protein, Adaptor Protein 
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having… Expand
National Institutes of Health

Related topics

Related topics

49 relations
ABI1 protein, humanFRS3 protein, humanProcess of secretionSH2 domain-containing leukocyte protein, 76-kDa
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Narrower (37)

ATG13 protein, humanATRIP protein, humanAbtb2 protein, ratAgtrap protein, mouse
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
Innate immune receptor signaling, united Innate immune receptors such as RIG-I, cGAS, and Toll-like receptors bind microbial… Expand
Highly Cited
2011
Highly Cited
2011
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
The genome is extensively transcribed into long intergenic noncoding RNAs (lincRNAs), many of which are implicated in gene… Expand
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Review
2011
Review
2011
Molecular mechanism and physiological functions of clathrin-mediated endocytosis
Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is packaged into vesicles with the aid of a… Expand
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Highly Cited
2006
Highly Cited
2006
Cryopyrin activates the inflammasome in response to toxins and ATP
A crucial part of the innate immune response is the assembly of the inflammasome, a cytosolic complex of proteins that activates… Expand
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Highly Cited
2005
Highly Cited
2005
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
Antiviral immunity against a pathogen is mounted upon recognition by the host of virally associated structures. One of these… Expand
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Review
2003
Review
2003
Signals for sorting of transmembrane proteins to endosomes and lysosomes.
Sorting of transmembrane proteins to endosomes and lysosomes is mediated by signals present within the cytosolic domains of the… Expand
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Review
2002
Review
2002
Lipopolysaccharide endotoxins.
Bacterial lipopolysaccharides (LPS) typically consist of a hydrophobic domain known as lipid A (or endotoxin), a nonrepeating… Expand
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Highly Cited
2002
Highly Cited
2002
Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling1
MyD88 is a Toll/IL-1 receptor (TIR) domain-containing adapter common to signaling pathways via Toll-like receptor (TLR) family… Expand
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Highly Cited
2000
Highly Cited
2000
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1.
Malfolded proteins in the endoplasmic reticulum (ER) induce cellular stress and activate c-Jun amino-terminal kinases (JNKs or… Expand
Highly Cited
1999
Highly Cited
1999
The p66shc adaptor protein controls oxidative stress response and life span in mammals
Gene mutations in invertebrates have been identified that extend life span and enhance resistance to environmental stresses such… Expand
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