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Adaptor Proteins, Signal Transducing

Known as: Adapter Signaling Protein, Signal Transducing Adaptor Protein, Adaptor Protein 
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Inflammasomes are multiprotein innate immune complexes that regulate caspase-dependent inflammation and cell death. Pattern… Expand
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Highly Cited
2015
Highly Cited
2015
Innate immune receptor signaling, united Innate immune receptors such as RIG-I, cGAS, and Toll-like receptors bind microbial… Expand
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Highly Cited
2011
Highly Cited
2011
The genome is extensively transcribed into long intergenic noncoding RNAs (lincRNAs), many of which are implicated in gene… Expand
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Highly Cited
2006
Highly Cited
2006
A crucial part of the innate immune response is the assembly of the inflammasome, a cytosolic complex of proteins that activates… Expand
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Highly Cited
2005
Highly Cited
2005
Antiviral immunity against a pathogen is mounted upon recognition by the host of virally associated structures. One of these… Expand
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Review
2003
Review
2003
Sorting of transmembrane proteins to endosomes and lysosomes is mediated by signals present within the cytosolic domains of the… Expand
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Review
2002
Review
2002
Bacterial lipopolysaccharides (LPS) typically consist of a hydrophobic domain known as lipid A (or endotoxin), a nonrepeating… Expand
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Highly Cited
2000
Highly Cited
2000
Malfolded proteins in the endoplasmic reticulum (ER) induce cellular stress and activate c-Jun amino-terminal kinases (JNKs or… Expand
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Highly Cited
2000
Highly Cited
2000
Estrogen rapidly activates the mitogen-activated protein kinases, Erk-1 and Erk-2, via an as yet unknown mechanism. Here… Expand
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Highly Cited
1999
Highly Cited
1999
Gene mutations in invertebrates have been identified that extend life span and enhance resistance to environmental stresses such… Expand
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