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SH2 domain-containing leukocyte protein, 76-kDa

Known as: SLP-76 signal Transducing adaptor proteins, SH2 Domain-Containing Leukocyte Protein, 76kD, Lymphocyte Cytosolic Protein 2 
Lymphocyte cytosolic protein 2 (533 aa, ~60 kDa) is encoded by the human LCP2 gene. This protein is involved in signal transduction.
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
OBJECTIVE To perform a genome-wide association study (GWAS) in Koreans in order to identify susceptibility loci for rheumatoid… Expand
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Highly Cited
2010
Highly Cited
2010
Although platelets appear by embryonic day 10.5 in the developing mouse, an embryonic role for these cells has not been… Expand
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Highly Cited
2008
Highly Cited
2008
Antigen-dependent T cell activation drives the formation of signaling microclusters containing the adaptor SLP-76. Costimulatory… Expand
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Highly Cited
2007
Highly Cited
2007
HPK1 is a Ste20-related serine-threonine kinase that inducibly associates with the adaptors SLP-76 and Gads after T cell receptor… Expand
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Highly Cited
2006
Highly Cited
2006
Developmental studies support a common origin for blood and endothelial cells, while studies of adult angiogenic responses… Expand
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Highly Cited
1999
Highly Cited
1999
ABSTRACT In the present study, we have addressed the role of the linker for activation of T cells (LAT) in the regulation of… Expand
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Highly Cited
1997
Highly Cited
1997
THE oncogenic protein Vav1,2 harbours a complex array of structural motifs, including leucine-rich, Dbl-homology, pleckstrin… Expand
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Highly Cited
1997
Highly Cited
1997
T cell activation stimulates p56(lck), p59(fyn), ZAP-70, Vav-SLP-76 binding, and IL-2 transcription. Major questions concern the… Expand
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Highly Cited
1997
Highly Cited
1997
Previous work has demonstrated that SLP-76, a Grb2-associated tyrosine-phosphorylated protein, augments Interleukin-2 promoter… Expand
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Highly Cited
1996
Highly Cited
1996
Two families of tyrosine kinases, the Src and Syk families, are required for T-cell receptor activation. While the Src kinases… Expand
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