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Alternative Splicing

Known as: Splicing, Alternative, Splicings, Alternative RNA, RNA Splicing, Alternative 
A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible… 
National Institutes of Health

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Related topics

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ABALON geneABALON wt AlleleApoptotic BCL2L1-Antisense Long Non-Coding RNA, humanGene Feature

Broader (1)

RNA Splicing

Papers overview

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Highly Cited
2002
Highly Cited
2002
Exon-specific RNAi: a tool for dissecting the functional relevance of alternative splicing.
The goal of functional genomics is to determine the function of each protein encoded by an organism. Typically, this is done by… 
Highly Cited
1997
Highly Cited
1997
DEPENDENCE OF INACTIVATION SUBUNIT IN THE KINETICS AND Ca2+ 1C α ENCODED BY EXONS 40-42 IN THE CARBOXYL-TERMINAL REGION Calcium
, 
Highly Cited
1992
Highly Cited
1992
Multiple Rh messenger RNA isoforms are produced by alternative splicing.
Three Rh-related cDNAs have been isolated from a human bone marrow cDNA library and by polymerase chain reaction (PCR… 
Highly Cited
1990
Highly Cited
1990
Identification of an additional member of the protein-tyrosine-phosphatase family: evidence for alternative splicing in the tyrosine phosphatase domain.
Protein-tyrosine-phosphatases (protein-tyrosine-phosphate phosphohydrolase, EC 3.13.48) have been implicated in the regulation of… 
Highly Cited
1988
Highly Cited
1988
Comparison of expression in hemopoietic cells by retroviral vectors carrying two genes
In order to identify factors that influence expression by retroviral vectors in hemopoietic cells, we have compared viral RNA… 
Highly Cited
1988
Highly Cited
1988
Differential splicing of MAG transcripts during CNS and PNS development.
Highly Cited
1988
Highly Cited
1988
Alternative splicing of tropomyosin pre-mRNAs in vitro and in vivo.
A single rat gene encodes both fibroblast TM-1 and skeletal muscle beta-tropomyosin by an alternative RNA-processing mechanism… 
Highly Cited
1987
Highly Cited
1987
Monoclonal antibodies in the analysis of fibronectin isoforms generated by alternative splicing of mRNA precursors in normal and transformed human cells
Recent results showing that a single fibronectin gene can give rise to several different mRNAs by alternative splicing have… 
Highly Cited
1987
Highly Cited
1987
The human U1-70K snRNP protein: cDNA cloning, chromosomal localization, expression, alternative splicing and RNA-binding.
We have isolated and sequenced cDNA clones encoding the human U1-70K snRNP protein, and have mapped this locus (U1AP1) to human… 
Highly Cited
1985
Highly Cited
1985
Expression of class I genes in the major histocompatibility complex: identification of eight distinct mRNAs in DBA/2 mouse liver
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