• Publications
  • Influence
Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy–negative individuals
The mRNA for the Duffy blood group antigen, the erythrocyte receptor for the Plasmodium vivax malaria parasite, has recently been cloned and shown to encode a widely expressed chemokine receptor.Expand
  • 650
  • 26
Plasmodium vivax clinical malaria is commonly observed in Duffy-negative Malagasy people
Malaria therapy, experimental, and epidemiological studies have shown that erythrocyte Duffy blood group-negative people, largely of African ancestry, are resistant to erythrocyte Plasmodium vivaxExpand
  • 306
  • 25
  • PDF
RhBG and RhCG, the putative ammonia transporters, are expressed in the same cells in the distal nephron.
Two nonerythroid homologs of the blood group Rh proteins, RhCG and RhBG, which share homologies with specific ammonia transporters in primitive organisms and plants, could represent members of a newExpand
  • 133
  • 16
  • PDF
Evidence that the red cell skeleton protein 4.2 interacts with the Rh membrane complex member CD47.
Rh(null) red cells are characteristically stomato-spherocytic. This and other evidence suggest that the Rh complex represents a major attachment site between the membrane lipid bilayer and theExpand
  • 107
  • 11
  • PDF
Genetic basis of the RhD-positive and RhD-negative blood group polymorphism as determined by Southern analysis
Several lines of evidence have previously indicated that the RhD, c, and E blood group antigens are most likely carried by three distinct but homologous red blood cell membrane proteins. To determineExpand
  • 260
  • 9
Molecular cloning and primary structure of the human blood group RhD polypeptide.
The RH (rhesus) blood group locus from RhD-positive donors is composed of two homologous structural genes, one of which encodes the Cc and Ee polypeptides, whereas the other, which is missing in theExpand
  • 268
  • 9
Rh proteins: key structural and functional components of the red cell membrane.
Rh (Rhesus) proteins (D, CcEe) are expressed in red cells (RBC) in association with other membrane proteins (RhAG, LW, CD47 and GPB). By interacting with the spectrin-based skeleton through proteinExpand
  • 113
  • 7
Transcript analysis of D category phenotypes predicts hybrid Rh D-CE-D proteins associated with alteration of D epitopes.
The RH blood group locus from RhD-positive donors is composed of two closely related genes, RHCE and RHD, encoding the Cc/Ee and D antigens, respectively. The major Rh antigen, D, is serologicallyExpand
  • 71
  • 6
αII-Spectrin Is Critical for Cell Adhesion and Cell Cycle*
Spectrins are ubiquitous scaffolding components of the membrane skeleton that organize and stabilize microdomains on both the plasma membrane and the intracellular organelles. By way of theirExpand
  • 49
  • 5
Molecular genetic basis of the human Rhesus blood group system
The Rhesus (RH) blood group locus is composed of two related structural genes, D and CcEe, that encode red cell membrane proteins carrying the D, Cc and Ee antigens. As demonstrated previously, theExpand
  • 259
  • 4