Interleukin 4 Receptor

Known as: Receptor, IL4, IL-4 Receptors, Receptors, IL 4 
Receptors present on a wide variety of hematopoietic and non-hematopoietic cell types that are specific for INTERLEUKIN-4. They are involved in… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
The interleukin 4 receptor (IL-4R) is a central mediator of T helper type 2 (TH2)–mediated disease and associates with either the… (More)
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Highly Cited
2008
Highly Cited
2008
T helper type 2 (TH2) cells are essential for humoral immunity and host defense. Interleukin 4 (IL-4) drives TH2 differentiation… (More)
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Highly Cited
2008
Highly Cited
2008
IL-13 and IL-4 are central T helper 2 (Th2) cytokines in the immune system and potent activators of inflammatory responses and… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND IL-4 mediates important proinflammatory functions in asthma, including induction of the IgE isotype switch, increased… (More)
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Review
1999
Review
1999
Interleukin-4 is a multifunctional cytokine that plays a critical role in the regulation of immune responses. Its effects depend… (More)
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Highly Cited
1999
Highly Cited
1999
IL-4 receptor alpha-chain-deficient (IL-4Ralpha-/-) mice were generated by homologous and site-specific recombination, using the… (More)
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Highly Cited
1997
Highly Cited
1997
IL-4 receptor alpha chain (IL-4Ralpha)-deficient mice were generated by gene-targeting in BALB/c embryonic stem cells. Mutant… (More)
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Highly Cited
1996
Highly Cited
1996
Interleukins 4 (IL-4) and 13 (IL-13) have been found previously to share receptor components on some cells, as revealed by… (More)
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Highly Cited
1993
Highly Cited
1993
Previously, Puri et al. (Puri, R. K., M. Ogata, P. Leland, G. M. Feldman, D. Fitzgerald, and I. Pastan. 1991. Cancer Res. 51:3011… (More)
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Highly Cited
1990
Highly Cited
1990
IL-4, a pleiotropic cytokine produced by T lymphocytes, plays an important role in immune responsiveness by regulating… (More)
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