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Interleukin 4 Receptor

Known as: Receptor, IL4, IL-4 Receptors, Receptors, IL 4 
Receptors present on a wide variety of hematopoietic and non-hematopoietic cell types that are specific for INTERLEUKIN-4. They are involved in… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Neuroinflammation is considered one of the cardinal features of Alzheimer’s disease (AD). Neuritic plaques composed of amyloid… Expand
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Highly Cited
2008
Highly Cited
2008
The interleukin 4 receptor (IL-4R) is a central mediator of T helper type 2 (TH2)–mediated disease and associates with either the… Expand
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Highly Cited
2008
Highly Cited
2008
T helper type 2 (TH2) cells are essential for humoral immunity and host defense. Interleukin 4 (IL-4) drives TH2 differentiation… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND IL-4 mediates important proinflammatory functions in asthma, including induction of the IgE isotype switch, increased… Expand
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Highly Cited
2000
Highly Cited
2000
The concept that IL-4 is the primary signal for Th2 lymphocyte differentiation has recently been put in doubt by studies in which… Expand
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Review
1999
Review
1999
Interleukin-4 is a multifunctional cytokine that plays a critical role in the regulation of immune responses. Its effects depend… Expand
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Highly Cited
1997
Highly Cited
1997
IL-4 receptor alpha chain (IL-4Ralpha)-deficient mice were generated by gene-targeting in BALB/c embryonic stem cells. Mutant… Expand
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Highly Cited
1996
Highly Cited
1996
Interleukins 4 (IL-4) and 13 (IL-13) have been found previously to share receptor components on some cells, as revealed by… Expand
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Highly Cited
1994
Highly Cited
1994
Interleukin-4 (IL-4) treatment of 32D cells overexpressing insulin receptor substrate 1 (IRS-1) causes prompt tyrosine… Expand
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Highly Cited
1990
Highly Cited
1990
IL-4, a pleiotropic cytokine produced by T lymphocytes, plays an important role in immune responsiveness by regulating… Expand
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