• Publications
  • Influence
Immunologic messenger molecules: cytokines, interferons, and chemokines.
Cytokines and chemokines are secreted proteins involved in numerous aspects of cell growth, differentiation, and activation. A prominent feature of these molecules is their effect on the immuneExpand
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The diagnosis and management of sinusitis: a practice parameter update.
These parameters were developed by the Joint Task Force on Practice Parameters, representing the American Academy of Allergy, Asthma and Immunology; the American College of Allergy, Asthma andExpand
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Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy
Asthma may develop secondary to the transcriptional dysregulation of T lymphocyte-derived cytokines. These cytokines influence IgE prodtiction. bone marrow stimulation, and allergic inflammation.Expand
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The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29.
Cytokines are involved in virtually every aspect of immunity and inflammation. A cascade of responses evolves after cytokine activation, although optimal function might ultimately involve severalExpand
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IL-10: evolving concepts.
  • L. Borish
  • Medicine, Biology
  • The Journal of allergy and clinical immunology
  • 1 March 1998
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2. Cytokines and chemokines.
  • L. Borish, J. Steinke
  • Biology, Medicine
  • The Journal of allergy and clinical immunology
  • 1 February 2003
Cytokines and chemokines are redundant secreted proteins with growth, differentiation, and activation functions that regulate and determine the nature of immune responses and control immune cellExpand
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Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial.
UNLABELLED Interleukin-4 mediates important proinflammatory functions in asthma, including induction of the IgE isotype switch, expression of VCAM-1 on endothelium, mucin production, 15-lipoxygenaseExpand
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Twelve-year survey of fatal reactions to allergen injections and skin testing: 1990-2001.
BACKGROUND Fatal reactions associated with skin testing and injection immunotherapy have not been surveyed in North America since 1989. OBJECTIVE A survey of fatal reactions related to skin testingExpand
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Interleukin-10 and transforming growth factor-beta promoter polymorphisms in allergies and asthma.
Interleukin-10 (IL-10) and transforming growth factor beta (TGF-beta) are inhibitory for B and T cells, IgE production, and mast cell proliferation, and they induce apoptosis in eosinophils. TheseExpand
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Case fatality and population mortality associated with anaphylaxis in the United States.
BACKGROUND Anaphylaxis is a serious allergic reaction that can cause death; however, the actual risk of death is unclear. OBJECTIVE We sought to estimate the case fatality rate amongExpand
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