• Publications
  • Influence
The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol.
STUDY OBJECTIVE To compare the safety of salmeterol xinafoate or placebo added to usual asthma care. DESIGN A 28-week, randomized, double-blind, placebo-controlled, observational study. SETTINGExpand
  • 1,062
  • 26
  • PDF
Sublingual immunotherapy: a comprehensive review.
Sublingual immunotherapy (SLIT) has been used with increasing frequency in Europe and is viewed with increasing interest by allergists in the United States. To address this interest, a Joint TaskExpand
  • 349
  • 15
Sublingual immunotherapy: World Allergy Organization position paper 2013 update
We have prepared this document, “Sublingual Immunotherapy: World Allergy Organization Position Paper 2013 Update”, according to the evidence-based criteria, revising and updating chapters of theExpand
  • 383
  • 13
  • PDF
Treatment of anaphylactic sensitivity to peanuts by immunotherapy with injections of aqueous peanut extract.
BACKGROUND Immediate hypersensitivity to peanuts is a frequent cause of anaphylactic reactions and deaths in children and adults. Currently, preventive treatment consists of avoidance, which isExpand
  • 517
  • 11
Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial.
UNLABELLED Interleukin-4 mediates important proinflammatory functions in asthma, including induction of the IgE isotype switch, expression of VCAM-1 on endothelium, mucin production, 15-lipoxygenaseExpand
  • 435
  • 11
An evidence-based analysis of house dust mite allergen immunotherapy: a call for more rigorous clinical studies.
BACKGROUND According to meta-analyses and reviews, subcutaneous allergen immunotherapy (SCIT) and sublingual allergen immunotherapy (SLIT) are beneficial in patients with allergic rhinitis (AR) andExpand
  • 113
  • 11
Onset and persistence of childhood asthma: predictors from infancy.
OBJECTIVE In a prospective study of children with a family history of asthma, asthma onset by 3 years of age was found previously to be positively associated with variables from the first year ofExpand
  • 293
  • 10
  • PDF
Fluticasone propionate/salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast.
BACKGROUND Asthma is a disease of chronic inflammation and bronchoconstriction. Inhaled corticosteroids (ICSs) provide important anti-inflammatory treatment but may not provide optimal control ofExpand
  • 224
  • 9
Burden of allergic rhinitis: allergies in America, Latin America, and Asia-Pacific adult surveys.
Allergic rhinitis (AR; also nasal allergies or "hay fever") is a chronic upper airway inflammatory disease that affects ∼60 million adults and children in the United States. The duration and severityExpand
  • 143
  • 9
Efficacy of soluble IL-4 receptor for the treatment of adults with asthma.
BACKGROUND IL-4 mediates important proinflammatory functions in asthma, including induction of the IgE isotype switch, increased expression of vascular cell adhesion molecule 1 and promotion ofExpand
  • 409
  • 8