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IL4R protein, human

Known as: IL4RA, interleukin 4 receptor, human, IL4R 
Interleukin-4 receptor subunit alpha (825 aa, ~90 kDa) is encoded by the human IL4R gene. This protein plays a role in both interleukin-4 signaling… 
National Institutes of Health

Related topics

Related topics

18 relations
Cytokine Receptor GeneCytokine Signaling ProcessIL4 Signaling PathwayIL4R gene

Broader (2)

Interleukin 4 ReceptorInterleukin-4 Receptor alpha Subunit

Papers overview

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Highly Cited
2004
Highly Cited
2004
Gene–gene interaction between interleukin‐4 and interleukin‐4 receptor α in Korean children with asthma
Background Interleukin‐4 receptor α (IL‐4Rα), which binds IL‐4 and IL‐13, is involved in signal transduction of those cytokines… 
Highly Cited
2001
Highly Cited
2001
Lack of association between atopic eczema and the genetic variants of interleukin‐4 and the interleukin‐4 receptor α chain gene: heterogeneity of genetic backgrounds on immunoglobulin E production in…
Background The genetic background of atopic eczema might be heterogeneous and there is a possibility that immunoglobulin (Ig)E… 
Highly Cited
2001
Highly Cited
2001
Aerosolized protein delivery in asthma: gamma camera analysis of regional deposition and perfusion.
Bioavailability of an aerosolized anti-inflammatory protein, soluble interleukin-4 receptor (IL-4R), was measured in patients… 
1999
1999
Lack of association of atopy/asthma and the interleukin‐4 receptor α gene in Japanese
Susceptibility to the development of atopic diseases is known to involve genetic factors. Several investigators have reported the… 
Review
1999
Review
1999
Soluble interleukin-4 receptor (sIL-4R) in allergic diseases
Abstract. The mediator interleukin-4 (IL-4) plays an important role in the development of allergic inflammatory responses. IL-4… 
Highly Cited
1997
Highly Cited
1997
Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain.
The cytokines interleukin (IL)-4 and IL-13 play a critical role in inducing Cepsilon germline transcripts and IgE isotype… 
1993
1993
Ligand-dependent activation of chimeric receptors with the cytoplasmic domain of the interleukin-3 receptor beta subunit (beta IL3).
1993
1993
Expression of IL-4 receptor on human T and B lymphocytes.
The expression of the interleukin-4 receptor on human blood and tonsil lymphocytes has been studied using a monoclonal antibody… 
1992
1992
The murine interleukin-4 receptor gene: genomic structure, expression and potential for alternative splicing.
The structure of the murine interleukin-4 receptor (mIL-4R) gene has been determined. The gene spans approximately 25 kilobases… 
1991
1991
Characterization and pharmacokinetic parameters of recombinant soluble interleukin-4 receptor.
The interleukin-4 receptor (IL-4R) is expressed as a 140-Kd membrane glycoprotein that binds IL-4 with high affinity. Recently… 
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