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IL4R wt Allele

Known as: Interleukin 4 Receptor wt Allele, Interleukin 4 Receptor, Alpha Gene, CD124 
Human IL4R wild-type allele is located within 16p11.2-12.1 and is approximately 35 kb in length. This allele, which encodes interleukin-4 receptor… 
National Institutes of Health

Related topics

Related topics

14 relations
16p11.2-12.1AsthmaAtopyCytokine Signaling Process

Broader (1)

IL4R gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Phenotypic changes of peripheral blood mononuclear cells upon corticosteroid treatment in idiopathic intermediate uveitis.
2016
2016
Polymorphisms of genes encoding interleukin-4 and its receptor in Iranian patients with juvenile idiopathic arthritis
As cytokines, including interleukin-4 (IL-4), seem to have a pivotal role in the pathogenesis of juvenile idiopathic arthritis… 
2015
2015
Deletion of IL-4Rα in the BALB/c mouse is associated with altered lesion topography and susceptibility to experimental autoimmune encephalomyelitis
Abstract The regulation of cytokine expression by immune deviation from a pro-inflammatory to anti-inflammatory or “regulatory… 
2012
2012
Microenvironment and Immunology Aptamer-Mediated Blockade of IL 4 R a Triggers Apoptosis of MDSCs and Limits Tumor Progression
In addition to promoting tumor progression andmetastasis by enhancing angiogenesis and invasion, myeloidderived suppressor cells… 
2011
2011
Single nucleotide polymorphisms in IL-4Ra, IL-13 and STAT6 genes occurs in brain glioma.
Gliomas are aggressive brain tumor. Association studies were consistent for an inverse association between asthma and allergic… 
2004
2004
Expression of interleukin 4 receptors in bronchial asthma patients who underwent specific immunotherapy.
2003
2003
No linkage or association of five polymorphisms in the interleukin-4 receptor alpha gene with atopic asthma in Italian families.
The literature contains conflicting reports on the association of common variants of the interleukin (IL)-4 receptor alpha (IL4RA… 
2002
2002
Multiple γc‐receptor expression in adult T‐cell leukemia
Abstract:  Constitutive expression of the IL‐2 receptor (IL‐2R) on adult T‐cell leukemia (ATL) cells and the presence of… 
2001
2001
A population genetics study of single nucleotide polymorphisms in the interleukin 4 receptor α (IL4RA) gene
Interleukin 4 (IL4) plays a critical role in T helper 2 (Th2) immune responses. Here we report a population genetics study of… 
1989
1989
Antigen-specific, but not natural killer, activity of T cell receptor-gamma delta cytotoxic T lymphocyte clones involves secretion of N alpha-benzyloxycarbonyl-L-lysine thiobenzyl ester serine…
Analysis of Ag specificity of TRC-gamma delta+ T cells in humans has been hampered by the fact that cloned lines of these cells… 
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