Interleukin-12

Known as: CLMF, IL12, Interleukin-12 p70 
Exhibiting a broad range of biological activities on T and natural killer cells, Interleukin-12 is a disulfide-bonded heterodimeric cytokine composed… (More)

Topic mentions per year

Topic mentions per year

1989-2017
010020019892017

Papers overview

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Highly Cited
2003
Highly Cited
2003
Interleukin (IL)-17 is a pro-inflammatory cytokine that is produced by activated T cells. Despite increasing evidence that high… (More)
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Highly Cited
1996
Highly Cited
1996
Mice with homologous disruption of the gene coding for either the p35 subunit or the p40 subunit of interleukin-12 (IL-12) and… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND In previous animal studies, interleukin 12 (IL 12) was shown to inhibit the growth of a wide spectrum of tumors in… (More)
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Highly Cited
1995
Highly Cited
1995
Several cytokines, in particular tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma), have been shown to be… (More)
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Highly Cited
1994
Highly Cited
1994
Peripheral blood mononuclear cells (PBMC) from human immunodeficiency virus (HIV)-infected patients, asymptomatic or with… (More)
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Highly Cited
1993
Highly Cited
1993
It has recently been demonstrated that in vivo administration of murine interleukin 12 (IL-12) to mice results in augmentation of… (More)
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Highly Cited
1993
Highly Cited
1993
Natural killer cell stimulatory factor or interleukin 12 (NKSF/IL-12) is a heterodimeric cytokine produced by monocytes… (More)
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Highly Cited
1993
Highly Cited
1993
Resistant C57BL/6 mice infected with Leishmania major are self-healing, whereas susceptible BALB/c mice fail to contain cutaneous… (More)
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Highly Cited
1992
Highly Cited
1992
Natural killer cell stimulatory factor (NKSF), or interleukin 12 (IL-12), is a 70-kD heterodimeric cytokine composed of two… (More)
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Highly Cited
1989
Highly Cited
1989
We have identified and purified a novel cytokine, NK cell stimulatory factor (NKSF), from the cell-free supernatant fluid of the… (More)
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