NHS-IL12 immunocytokine

Known as: Immunocytokine NHS-IL12, NHS-IL12 
A fusion protein consisting of the heavy-chains of the human antibody NHS76, raised against DNA released by necrotic tumor cells, and fused to two… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
02419932017

Papers overview

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2016
2016
NHS-IL12 is an immunocytokine targeting necrotic tumour areas. IL12 shows anti-tumour activity. As local irradiation might induce… (More)
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2014
2014
Targeted delivery of IL-12 might turn this cytokine into a safer, more effective cancer therapeutic. Here we describe a novel… (More)
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2011
2011
PURPOSE The goal of the study was to engineer a form of interleukin 2 (IL-2) that, when delivered as a tumor-specific antibody… (More)
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2010
2010
BACKGROUND L19-IL2, a tumour-targeting immunocytokine composed of the recombinant human antibody fragment L19 (specific to the… (More)
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2009
2009
To enhance the efficacy of a therapeutic immunisation strategy against human papillomavirus-induced cervical cancer we evaluated… (More)
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2007
2007
OBJECTIVES Replication-competent, vesicular stomatitis virus (VSV) has been demonstrated to be an effective oncolytic agent in a… (More)
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2005
2005
Interleukin (IL)-12 is a key factor for inducing cellular immune responses, which play a central role in the eradication of… (More)
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2005
2005
The Semliki Forest virus (SFV) vector is an RNA-based suicide expression vector that has been used experimentally for tumour… (More)
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2005
2005
Injection of DNA via electric pulses into targeted tissues is referred to as electrotransfer. Intratumoral electrotransfer of the… (More)
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