Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 227,741,320 papers from all fields of science
Search
Sign In
Create Free Account
Insulin Receptor Substrate-2 Protein
Known as:
Insulin Receptor Substrate 2
, Insulin Receptor Substrate 2 Protein
, Insulin Receptor Substrate-2
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
3 relations
IRS2 gene
Narrower (1)
IRS2 protein, human
Broader (1)
Insulin Receptor Substrate Proteins
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The TORC1-activated Proteins, p70S6K and GRB10, Regulate IL-4 Signaling and M2 Macrophage Polarization by Modulating Phosphorylation of Insulin Receptor Substrate-2*
K. Warren
,
Xi Fang
,
N. Gowda
,
Joshua J Thompson
,
N. Heller
Journal of Biological Chemistry
2015
Corpus ID: 21369945
Lung M2 macrophages are regulators of airway inflammation, associated with poor lung function in allergic asthma. Previously, we…
Expand
2013
2013
Nutritional Intervention Restores Muscle but Not Kidney Phenotypes in Adult Calcineurin Aα Null Mice
K. Madsen
,
R. Reddy
,
S. Price
,
Clintoria R. Williams
,
J. Gooch
PLoS ONE
2013
Corpus ID: 1451954
Mice lacking the α isoform of the catalytic subunit of calcineurin (CnAα) were first reported in 1996 and have been an important…
Expand
2012
2012
JNK3 Maintains Expression of the Insulin Receptor Substrate 2 (IRS2) in Insulin-Secreting Cells: Functional Consequences for Insulin Signaling
S. Abdelli
,
C. Bonny
PLoS ONE
2012
Corpus ID: 571703
We have recently shown that silencing of the brain/islet specific c-Jun N-terminal Kinase3 (JNK3) isoform enhances both basal and…
Expand
2011
2011
Glucagon-like peptide-1 and candesartan additively improve glucolipotoxicity in pancreatic β-cells.
Hong-wei Wang
,
M. Mizuta
,
Y. Saitoh
,
K. Noma
,
H. Ueno
,
M. Nakazato
Metabolism: Clinical and Experimental
2011
Corpus ID: 45890408
2011
2011
IRS-2 deficiency in macrophages promotes their accumulation in the vascular wall.
T. Mita
,
K. Azuma
,
+11 authors
H. Watada
Biochemical and Biophysical Research…
2011
Corpus ID: 3468625
2008
2008
Comment on "Brain IRS2 Signaling Coordinates Life Span and Nutrient Homeostasis"
C. Selman
,
Steven J. Lingard
,
D. Gems
,
L. Partridge
,
D. Withers
Science
2008
Corpus ID: 850443
Taguchi et al. (Reports, 20 July 2007, p. 369) reported that mice heterozygous for a null mutation in insulin receptor substrate…
Expand
Highly Cited
2008
Highly Cited
2008
Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.
R. Granata
,
F. Settanni
,
+12 authors
E. Ghigo
Diabetes
2008
Corpus ID: 30121703
OBJECTIVE Obestatin is a newly discovered peptide encoded by the ghrelin gene whose biological functions are poorly understood…
Expand
2003
2003
Oestrogen improves glucose metabolism and insulin signal transduction in HepG2 cells
P. Xie
,
Mei-lian Liu
,
+4 authors
Hui-ping Song
Clinical and Experimental Pharmacology and…
2003
Corpus ID: 7387971
1. Many clinical studies have suggested a relationship between oestrogen and insulin sensitivity. In the present study, HepG2…
Expand
2000
2000
Developmental Expression of Insulin Receptor Substrate-2 During Dimethylsulfoxide-Induced Differentiation of Human HL-60 Cells1
D. Schacher
,
R. Vanhoy
,
+4 authors
K. Kelley
Journal of Immunology
2000
Corpus ID: 13194391
Insulin receptor substrate-2 (IRS-2) is phosphorylated on tyrosine by a number of cytokine receptors and is implicated in the…
Expand
Highly Cited
1996
Highly Cited
1996
Interaction of Insulin Receptor Substrate-2 (IRS-2) with the Insulin and Insulin-like Growth Factor I Receptors
Weimin He
,
A. Craparo
,
+4 authors
T. A. Gustafson
Journal of Biological Chemistry
1996
Corpus ID: 12092880
Insulin receptor substrate 2 (IRS-2) has recently been shown to be a substrate of the insulin receptor (IR). In this study we…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE