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Insulin Receptor Substrate-2 Protein

Known as: Insulin Receptor Substrate 2, Insulin Receptor Substrate 2 Protein, Insulin Receptor Substrate-2 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Mice overexpressing acylCoA:diacylglycerol (DAG) acyltransferase 2 in the liver (Liv-DGAT2) have been shown to have normal… Expand
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Highly Cited
2008
Highly Cited
2008
Differences in reported life span of mice heterozygous for a null allele of the insulin receptor substrate–2 (Irs2) might involve… Expand
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Review
2008
Review
2008
Understanding how IL-4 and IL-13 signaling differ could result in the development of better anti-inflammatory therapies… Expand
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Highly Cited
2007
Highly Cited
2007
We analyzed the PI3K-AKT signaling cascade in a cohort of sarcomas and found a marked induction of insulin receptor substrate-2… Expand
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Highly Cited
2003
Highly Cited
2003
The insulin receptor substrate-2 (Irs2) branch of the insulin/IGF signaling system coordinates peripheral insulin action and… Expand
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Highly Cited
2002
Highly Cited
2002
Diabetes is caused by an absolute (type 1) or relative (type 2) deficiency of insulin-producing beta cells. The mechanisms… Expand
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Highly Cited
2002
Highly Cited
2002
Patients with type 1 diabetes are identified after the onset of the disease, when β cell destruction is almost complete. β cell… Expand
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Highly Cited
2000
Highly Cited
2000
Severe dietary restriction, catabolic states and even short-term caloric deprivation impair fertility in mammals. Likewise… Expand
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Highly Cited
1998
Highly Cited
1998
Insulin receptor substrate-2 (IRS-2) is a multisite docking protein implicated in mitogenic signaling after activation of the… Expand
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Highly Cited
1996
Highly Cited
1996
Insulin receptor substrate 2 (IRS-2) has recently been shown to be a substrate of the insulin receptor (IR). In this study we… Expand
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