Insulin Receptor Substrate-2 Protein

Known as: Insulin Receptor Substrate 2, Insulin Receptor Substrate 2 Protein, Insulin Receptor Substrate-2 
 
National Institutes of Health

Papers overview

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2011
2011
Insulin has been shown to impact on learning and memory in both humans and animals, but the downstream signaling mechanisms… (More)
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2005
2005
De-regulations in insulin and insulin-like growth factor (IGF) pathways may contribute to hepatocellular carcinoma. Although… (More)
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Highly Cited
2003
Highly Cited
2003
The insulin receptor substrate-2 (Irs2) branch of the insulin/IGF signaling system coordinates peripheral insulin action and… (More)
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Highly Cited
2002
Highly Cited
2002
Diabetes is caused by an absolute (type 1) or relative (type 2) deficiency of insulin-producing beta cells. The mechanisms… (More)
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Highly Cited
2001
Highly Cited
2001
Insulin-like growth factors (IGFs) regulate breast cancer cell proliferation, protect cells from apoptosis, and enhance… (More)
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Highly Cited
2000
Highly Cited
2000
Severe dietary restriction, catabolic states and even short-term caloric deprivation impair fertility in mammals. Likewise… (More)
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1999
1999
Insulin receptor substrate-2 (IRS-2) belongs to a family of cytoplasmic adaptor proteins, which link insulin, IGF-1, and cytokine… (More)
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1998
1998
Insulin receptor substrate-2 (IRS-2) is a multisite docking protein implicated in mitogenic signaling after activation of the… (More)
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Highly Cited
1997
Highly Cited
1997
We have recently shown that leptin mimicks insulin effects on glucose transport and glycogen synthesis through a… (More)
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1996
1996
In this report, we demonstrate that insulin receptor substrate-2 (IRS-2) is tyrosyl-phosphorylated following stimulation of 3T3… (More)
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