Insulin Receptor Substrate-2 Protein
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Mice overexpressing acylCoA:diacylglycerol (DAG) acyltransferase 2 in the liver (Liv-DGAT2) have been shown to have normal… Expand Differences in reported life span of mice heterozygous for a null allele of the insulin receptor substrate–2 (Irs2) might involve… Expand Understanding how IL-4 and IL-13 signaling differ could result in the development of better anti-inflammatory therapies… Expand We analyzed the PI3K-AKT signaling cascade in a cohort of sarcomas and found a marked induction of insulin receptor substrate-2… Expand The insulin receptor substrate-2 (Irs2) branch of the insulin/IGF signaling system coordinates peripheral insulin action and… Expand Diabetes is caused by an absolute (type 1) or relative (type 2) deficiency of insulin-producing beta cells. The mechanisms… Expand Patients with type 1 diabetes are identified after the onset of the disease, when β cell destruction is almost complete. β cell… Expand Severe dietary restriction, catabolic states and even short-term caloric deprivation impair fertility in mammals. Likewise… Expand Insulin receptor substrate-2 (IRS-2) is a multisite docking protein implicated in mitogenic signaling after activation of the… Expand In this report, we demonstrate that insulin receptor substrate-2 (IRS-2) is phosphorylated on tyrosine following treatment of UT… Expand