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Insulin Receptor Substrate-2 Protein

Known as: Insulin Receptor Substrate 2, Insulin Receptor Substrate 2 Protein, Insulin Receptor Substrate-2 
National Institutes of Health

Related topics

Related topics

3 relations
IRS2 gene

Narrower (1)

IRS2 protein, human

Broader (1)

Insulin Receptor Substrate Proteins

Papers overview

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2015
2015
The TORC1-activated Proteins, p70S6K and GRB10, Regulate IL-4 Signaling and M2 Macrophage Polarization by Modulating Phosphorylation of Insulin Receptor Substrate-2*
Lung M2 macrophages are regulators of airway inflammation, associated with poor lung function in allergic asthma. Previously, we… 
2013
2013
Nutritional Intervention Restores Muscle but Not Kidney Phenotypes in Adult Calcineurin Aα Null Mice
Mice lacking the α isoform of the catalytic subunit of calcineurin (CnAα) were first reported in 1996 and have been an important… 
2012
2012
JNK3 Maintains Expression of the Insulin Receptor Substrate 2 (IRS2) in Insulin-Secreting Cells: Functional Consequences for Insulin Signaling
We have recently shown that silencing of the brain/islet specific c-Jun N-terminal Kinase3 (JNK3) isoform enhances both basal and… 
2011
2011
Glucagon-like peptide-1 and candesartan additively improve glucolipotoxicity in pancreatic β-cells.
2011
2011
IRS-2 deficiency in macrophages promotes their accumulation in the vascular wall.
2008
2008
Comment on "Brain IRS2 Signaling Coordinates Life Span and Nutrient Homeostasis"
Taguchi et al. (Reports, 20 July 2007, p. 369) reported that mice heterozygous for a null mutation in insulin receptor substrate… 
Highly Cited
2008
Highly Cited
2008
Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.
OBJECTIVE Obestatin is a newly discovered peptide encoded by the ghrelin gene whose biological functions are poorly understood… 
2003
2003
Oestrogen improves glucose metabolism and insulin signal transduction in HepG2 cells
1. Many clinical studies have suggested a relationship between oestrogen and insulin sensitivity. In the present study, HepG2… 
2000
2000
Developmental Expression of Insulin Receptor Substrate-2 During Dimethylsulfoxide-Induced Differentiation of Human HL-60 Cells1
Insulin receptor substrate-2 (IRS-2) is phosphorylated on tyrosine by a number of cytokine receptors and is implicated in the… 
Highly Cited
1996
Highly Cited
1996
Interaction of Insulin Receptor Substrate-2 (IRS-2) with the Insulin and Insulin-like Growth Factor I Receptors
Insulin receptor substrate 2 (IRS-2) has recently been shown to be a substrate of the insulin receptor (IR). In this study we… 
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