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IRS2 gene

Known as: INSULIN RECEPTOR SUBSTRATE 2, IRS2, Insulin Receptor Substrate 2 Gene 
This gene is involved in signal transduction and is associated with Diabetes Mellitus.
National Institutes of Health

Related topics

Related topics

5 relations
Diabetes MellitusIRS2 protein, humanInsulin Receptor Substrate-2 ProteinSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Pyrroline-5-carboxylate reductase 2 (PYCR2), which associates with insulin receptor substrate 2 (IRS2) suppresses apoptosis of various cell types.
2015
2015
IRS 2 Copy Number Gain , KRAS and BRAF Mutation Status as Predictive Biomarkers for Response to the IGF-1 R / IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines
Insulin-like growth factor receptor 1 (IGF-1R)–targeting therapies are currently at an important crossroad given the low clinical… 
2015
2015
Mecanismos moleculares implicados en las alteraciones metabólicas inducidas por la suplementación subcrónica de fructosa líquida: estrés de retículo, autofagia y resistencia a la insulina
En las ultimas decadas se ha observado un aumento muy notable de la prevalencia de enfermedades metabolicas como la obesidad, el… 
2015
2015
Copy Number Gain , KRAS and BRAF Mutation Status as Predictive Biomarkers for Response to the IGF-1 R / IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines
Insulin-like growth factor receptor 1 (IGF-1R)–targeting therapies are currently at an important crossroad given the low clinical… 
2014
2014
The G1057D Polymorphism of Insulin Receptor Substrate-2 (IRS2) Gene With Type 2 Diabetes in the Turkish population
Amac: Insulin reseptor substrati (IRS) proteini, hedef dokulara insulin sinyalinin iletilmesinde kritik bir oneme sahiptir. IRS-2… 
2010
2010
By inhibiting insulin receptor substrate 2 (irs2) and transcription factor e3 (tfe3) natural antisense transcripts treating related diseases IRS2
The present invention relates to regulation of insulin receptor substrate (of IRS2) 2 expression polynucleotide and / or function… 
2010
2010
Treatment of transcription factor e3 TFE3 by inhibition of the natural antisense transcript for (TFE3) and insulin receptor substrate 2 (IRS2) related disease
The present invention is particularly transcription factor E3 (TFE3) and / or insulin receptor substrate 2 natural antisense… 
2010
2010
By inhibiting transcription factor for e3 (tfe3) natural antisense transcript treating TFE3 protein and insulin receptor substrate 2 (irs2) related diseases
The present invention relates to antisense oligonucleotides, specifically, by targeting the transcription factor E3 (of TFE3) and… 
2007
2007
The association of insulin receptor substrate 2 gene polymorphism with type 2 diabetes and its related metabolism
Objective To study the genotype distribution of insulin receptor substrate-2(IRS-2)gene 1057G/A polymorphism in Han population… 
2004
2004
IRS 2 takes center stage in the development of type 2 diabetes
886 The Journal of Clinical Investigation http://www.jci.org Volume 114 Number 7 October 2004 sumably, despite high local… 
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