IRS2 gene

Known as: INSULIN RECEPTOR SUBSTRATE 2, IRS2, Insulin Receptor Substrate 2 Gene 
This gene is involved in signal transduction and is associated with Diabetes Mellitus.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2018
0246819852018

Papers overview

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2013
2013
Copy number alterations are frequently found in colorectal cancer (CRC), and recurrent gains or losses are likely to correspond… (More)
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2010
2010
BACKGROUND Reduced insulin and insulin-like growth factor-1 (IGF-1) signaling extends the life span of invertebrate and mammals… (More)
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2008
2008
OBJECTIVE beta-Cell failure is an essential component of all types of diabetes, and the insulin receptor substrate 2 (IRS2… (More)
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2008
2008
Obesity has consistently been associated with postmenopausal breast cancer risk. Proteins that are secreted by adipose tissue or… (More)
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2008
2008
Clinical evidence has shown a correlation between Parkinson's disease (PD) and Type 2 Diabetes (T2D), as abnormal glucose… (More)
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Highly Cited
2007
Highly Cited
2007
Chronic morphine administration (via subcutaneous pellet) decreases the size of dopamine neurons in the ventral tegmental area… (More)
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Highly Cited
2005
Highly Cited
2005
In type 2 diabetes, the beta cells of the pancreas fail to produce enough insulin to meet the body's demand, in part because of… (More)
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2005
2005
BACKGROUND As cellular proliferation is central to the carcinogenic process, pathways that regulate proliferation may be… (More)
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Highly Cited
2004
Highly Cited
2004
INTRODUCTION Insulin, insulin-like growth factor (IGF), and IGF binding protein (IGFBP) are involved in cell growth and… (More)
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2003
2003
In order to understand the role of the insulin receptor substrate-2 (IRS2) gene (chromosome region: 13q34) in obesity, a complex… (More)
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