Skip to search formSkip to main contentSkip to account menu

IRS2 gene

Known as: INSULIN RECEPTOR SUBSTRATE 2, IRS2, Insulin Receptor Substrate 2 Gene 
This gene is involved in signal transduction and is associated with Diabetes Mellitus.
National Institutes of Health

Related topics

Related topics

5 relations
Diabetes MellitusIRS2 protein, humanInsulin Receptor Substrate-2 ProteinSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Early-Onset Diabetes Mellitus in a Patient With a Chromosome 13q34qter Microdeletion Including IRS2
Abstract Diabetes mellitus is a multifactorial disease caused by a complex interaction of environmental and genetic factors. Some… 
2016
2016
The upregulation of miRNA-146a inhibited biological behaviors of ESCC through inhibition of IRS2
In recent years, microRNAs, also called as miRNAs, play an important role in carcinogenesis, and the dysregulation of miRNAs is… 
2015
2015
Plk1 phosphorylation of IRS2 prevents premature mitotic exit via AKT inactivation.
Insulin receptor substrate (IRS) proteins play important roles by acting as a platform in transducing signals from transmembrane… 
2014
2014
CRFR1 activation protects against cytokine-induced β-cell death.
During the development of diabetes β-cells are exposed to elevated concentrations of proinflammatory cytokines, TNFα and IL1… 
2012
2012
Influence of the Gly1057Asp variant of the insulin receptor substrate 2 (IRS2) on insulin resistance and relationship with epicardial fat thickness in the elderly
2010
2010
Polymorphism Study of the Insulin Receptor Substrate IRS1 and IRS2 Genes Associated with Type 2 Diabetes in Ethnic Groups of Djerba Island
Aim: We aimed to evaluate the influence of the Gly972 Arg and Ala513Pro variants of the insulin receptor substrate1 gene (IRS1… 
2009
2009
Gene Silencing of Phogrin Unveils Its Essential Role in Glucose-Responsive Pancreatic β-Cell Growth
OBJECTIVE—Phogrin and IA-2, autoantigens in insulin-dependent diabetes, have been shown to be involved in insulin secretion in… 
2009
2009
Insulin receptor substrate 2 plays important roles in 17β-estradiol-induced bone formation
Background: Discovering the mechanisms of the estrogen effects on the osteoblasts is very important for the development of new… 
2008
2008
Bioactive Peptides Control Receptor for Advanced Glycated End Product-Induced Elevation of Kidney Insulin Receptor Substrate 2 and Reduce Albuminuria in Diabetic Mice
BACKGROUND/AIMS Sixteen-week-old db/db mice exhibit significantly elevated blood glucose and albuminuria. Kidney mesangial cell… 
2007
2007
A dominant role for glucose in beta cell compensation of insulin resistance.
Increased insulin secretion and expansion of pancreatic beta cell mass work together to maintain normal glucose levels when… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)