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IRS2 protein, human
Known as:
insulin receptor substrate 2, human
, IRS2
, IRS-2 protein, human
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Insulin receptor substrate 2 (1338 aa, ~137 kDa) is encoded by the human IRS2 gene. This protein is involved in insulin-dependent signal transduction…
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National Institutes of Health
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Related topics
Related topics
8 relations
Adaptor Signaling Protein Gene
IRS2 gene
Signal Transduction
Signaling Pathway Gene
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Broader (2)
Insulin Receptor Substrate Proteins
Insulin Receptor Substrate-2 Protein
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism.
C. Taniguchi
,
K. Ueki
,
C. Kahn
Journal of Clinical Investigation
2016
Corpus ID: 36175153
4 3 8 7 jci.org Volume 126 Number 11 November 2016 Retraction Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of…
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2012
2012
Glucose and lipid metabolism in human skeletal muscle
Paulina Skrobuk
2012
Corpus ID: 20885415
Insulin resistance is characterized by a blunted biological response to insulin, and it is the hallmark of obesity and type 2…
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2008
2008
The effect of high-fat diet on IRS-1 and IRS-2 expression of fatty liver in rat
Q. Liu
2008
Corpus ID: 101408135
Objective To explore the effect of high-fat diet on IRS-1 and IRS-2 expressions of fatty liver in rat. Methods After the rats…
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2007
2007
The direct involvement of SirT 1 in insulin-induced IRS-2 tyrosine phosphorylation
Jiandi Zhang
2007
Corpus ID: 32373148
NAD-dependent Sir2 family deacetylases and insulin signaling pathway are both conserved across species to regulate aging process…
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2006
2006
Erratum: Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet β-cells (Journal of Biological Chemistry (2006) 281, (15884-15892))
M. K. Lingohr
,
I. Briaud
,
+4 authors
C. Rhodes
2006
Corpus ID: 90509997
2005
2005
Erratum: Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism (Journal of Clinical Investigation (2005) 115 (718-727) DOI: 10.1172/JCI200523187)
C. Taniguchi
,
K. Ueki
,
C. Kahn
2005
Corpus ID: 78133353
2005
2005
New mechanism Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism
C. Lévy‐Marchal
2005
Corpus ID: 3938364
Insulin resistance and related disorders have proven to be a matter of concern for pediatricians in recent years. This is…
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2003
2003
Rosiglitazone reverses insulin secretion altered by chronic exposure to free fatty acid via IRS-2-associated phosphatidylinositol 3-kinase pathway.
Li Yang
,
Hanxiang An
,
Xiu-Ling Deng
,
Lulu Chen
,
Zhuoran Li
Acta Pharmacologica Sinica
2003
Corpus ID: 12632019
AIM To study the effect of rosiglitazone (RSG) on insulin secretion in isolated pancreatic islets under chronic exposure to free…
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2002
2002
GTK Tyrosine Kinase-induced Alteration of IRS-protein Signalling in Insulin Producing Cells
C. Annerén
,
M. Welsh
Molecular Medicine
2002
Corpus ID: 18866321
BackgroundInsulin receptor substrate proteins (IRS) mediate various effects of insulin, including regulation of glucose…
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1996
1996
Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT 4 exocytosis in 3 T 3L 1 cells
Jing Yang
,
J. Clarke
,
P. Young
,
M. Kasuga
,
G. Holman
1996
Corpus ID: 41432214
Glucose transporters (GLUTs) are continuously recycled in 3T3L1 cells and so insulin, through its action on phosphatidylinositol…
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