Insulin Receptor Substrate Proteins

Known as: IRS Signaling Adaptor Proteins, Insulin Receptor Substrate Proteins [Chemical/Ingredient] 
A structurally-related group of signaling proteins that are phosphorylated by the INSULIN RECEPTOR PROTEIN-TYROSINE KINASE. The proteins share an N… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2016
0119972016

Papers overview

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2015
2015
BACKGROUND Polycystic ovary syndrome (PCOS) is the commonest endocrinopathy in women of reproductive age. The patients often… (More)
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2013
2013
The Drosophila insulin receptor (DInR) regulates a diverse array of biological processes including growth, axon guidance, and… (More)
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Review
2012
Review
2012
The insulin receptor substrate proteins IRS1 and IRS2 are key targets of the insulin receptor tyrosine kinase and are required… (More)
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2009
2009
Adipocyte insulin resistance can be caused by proximal insulin signaling defects but also from postreceptor mechanisms, which in… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Mammalian target of rapamycin (mTOR) and its downstream target S6 kinase 1 (S6K1) mediate nutrient-induced insulin… (More)
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Review
2008
Review
2008
The insulin-like growth factor (IGF) pathway is involved in the normal control of fetal development, tissue growth, and… (More)
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Review
2007
Review
2007
Skeletal muscle is able not only to increase its mass as an adaptation to mechanical loading generated by and imposed upon muscle… (More)
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2005
2005
The growth factor IGF-I is critical for normal human somatic growth and development. Growth factor receptor-bound protein (Grb)10… (More)
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2002
2002
BACKGROUND Insulin receptor substrate proteins (IRS) mediate various effects of insulin, including regulation of glucose… (More)
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1997
1997
Interleukin (IL)-4 is a cytokine that regulates both the growth and differentiation of hematopoietic cells. Its ligand binding… (More)
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