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  • Charles L. Raison, Robert Dantzer, +6 authors Andrew H Miller
  • Biology, Medicine
  • Molecular Psychiatry
  • 2010 (First Publication: 21 October 2009)
  • Cytokine-induced activation of indoleamine 2,3-dioxygenase (IDO) catabolizes L-tryptophan (TRP) into L-kynurenine (KYN), which is metabolized to quinolinic acid (QUIN) and kynurenic acid (KA). QUINExpand
  • Jason C. O’Connor, Caroline André, +6 authors Robert Dantzer
  • Biology, Medicine
  • The Journal of Neuroscience
  • 2009 (First Publication: 1 April 2009)
  • Although the tryptophan-degrading enzyme, indoleamine 2,3-dioxygenase (IDO), is a pivotal mediator of inflammation-induced depression, its mechanism of regulation has not yet been investigated inExpand