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Insulin-Like Growth Factor-Binding Protein 4, human

Known as: IGFBP-4, IGF Binding Protein 4, Insulin-Like Growth Factor-Binding Protein 4 
Insulin-like growth factor-binding protein 4 (258 aa, ~28 kDa) is encoded by the human IGFBP4 gene. This protein plays a role in both insulin-like… 
National Institutes of Health

Related topics

Related topics

8 relations
IGFBP4 geneIGFBP4 wt AlleleInhibition of Cell ProliferationLigand Binding

Broader (1)

Insulin-Like Growth Factor Binding Protein 4

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Effects of estradiol on transcriptional profiles in atherosclerotic iliac arteries in ovariectomized cynomolgus macaques
ObjectiveThis study aimed to assess the in vivo effects of estradiol treatment on arterial gene expression in atherosclerotic… 
2010
2010
[The effect of tobacco smoking on serum concentration of IGF-I and its binding proteins IGFBP-3 and IGFBP-4 in pregnant women].
However smoking during pregnancy has been show to result in growth restriction of the fetus but the mechanism by which this… 
Highly Cited
2004
Highly Cited
2004
Paradoxical Actions of Endogenous and Exogenous Insulin-like Growth Factor-binding Protein-5 Revealed by RNA Interference Analysis*
Insulin-like growth factor-binding protein-5 (IGFBP-5) is abundantly expressed in bone cells. To determine the physiological role… 
2001
2001
Binding Protein-3-Selective Insulin-Like Growth Factor I Variants: Engineering, Biodistributions, and Clearance.
Insulin-like growth factor I (IGF-I) is a potent anabolic peptide that mediates most of its pleiotropic effects through… 
2001
2001
The transfection-induced overexpression of IGF-binding protein-4 affects the secretory activity of porcine ovarian granulosa cells and their response to hormones and IGF-I.
The aim of our studies was to examine whether IGF-binding protein (IGFBP)-4 is involved in the control of the secretion of… 
1999
1999
Insulin-Like Growth Factor Binding Protein-4 Proteolytic Degradation in Ovine Preovulatory Follicles: Studies of Underlying Mechanisms1.
The regulation of insulin-like growth factor binding protein (IGFBP)-4 proteolytic degradation by insulin-like growth factors… 
1996
1996
Immunohistochemical localization of insulin-like growth factor binding protein-1, -3 and -4 in human fetal tissues and their analysis in media from fetal tissue explants.
The actions of insulin-like growth factor (IGF) II that are important in the regulation of fetal growth and development, are… 
Highly Cited
1994
Highly Cited
1994
The insulin-like growth factor system in human peritoneal fluid: its effects on endometrial stromal cells and its potential relevance to endometriosis.
Peritoneal fluid (PF) lines the abdomen and pelvis and is believed to contain growth factors that stimulate endometriosis, a… 
1994
1994
Differential effects of thermal injury on circulating insulin-like growth factor binding proteins in burn patients
The results of this report provide evidence that insulin-like growth factor-1 binding proteins (IGFBPs) in human sera are… 
1991
1991
Insulin-like growth factor binding proteins (IGFBPs) in acromegaly.
Hypersecretion of growth hormone (GH) is the principal feature of acromegaly and is accompanied by an excess of IGF-I production… 
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