Insulin-Like Growth Factor-Binding Protein 4, human

Known as: IGFBP-4, IGF Binding Protein 4, Insulin-Like Growth Factor-Binding Protein 4 
Insulin-like growth factor-binding protein 4 (258 aa, ~28 kDa) is encoded by the human IGFBP4 gene. This protein plays a role in both insulin-like… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
024619922018

Papers overview

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2014
2014
Growth in teleosts is controlled in large part by the activities of the growth hormone (Gh)/insulin-like growth factor (Igf… (More)
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2011
2011
BACKGROUND We previously reported that the degradation of prohibitin by the SCF(Skp2B) ubiquitin ligase results in a defect in… (More)
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2011
2011
The Wnt/β-catenin signaling pathway is inactivated by Wnt antagonists in most cancers and IGFBP-4 is an antagonist of the Wnt… (More)
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2009
2009
Background:Insulin-like growth factor 1 (IGF1) promotes breast cancer and disease progression. Bioavailability of IGF1 is… (More)
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2005
2005
PTEN is a tumor suppressor gene that is frequently mutated or deleted in a variety of human cancers including human gastric… (More)
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2003
2003
IGFBP-4 is an inhibitor of IGF-I in bone. We show that TGF-beta regulates IGFBP-4 and enhances IGF-I-stimulated growth of… (More)
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2002
2002
The insulin-like growth factor binding proteins (IGFBPs) have IGF-independent differential effects on cell function. We… (More)
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2001
2001
Insulin-like growth factors (IGFs) are important growth regulators of both normal and malignant prostate cells. Their action is… (More)
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2001
2001
Insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) is a potent inhibitor of IGF actions in vitro. However, we found… (More)
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1994
1994
Insulin-like growth factor binding protein 4 (IGFBP-4) is secreted by normal human osteoblast-like cells (hOB) and is a potent… (More)
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