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Insulin-Like Growth Factor Binding Protein 4

Known as: Insulin Like Growth Factor Binding Protein 4, IGFBP-4, IGF Binding Protein 4 
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at… 
National Institutes of Health

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IGFBP4 geneIGFBP4 wt AlleleIn BloodProcess of secretion

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Insulin-Like Growth Factor-Binding Protein 4, human

Papers overview

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2011
2011
Growth factor and cytokine interactions in myogenesis. Part II. Expression of IGF binding proteins and protein kinases essential for myogenesis in mouse C2C12 myogenic cells exposed to TNF-alpha and…
The aim of the study was to examine potential interactions among IGF-I and proinflammatory cytokines, TNF-alpha and IFN-gamma, in… 
2006
2006
Insulin‐like growth factor binding proteins: regulation in chronic active plaques in multiple sclerosis and functional analysis of glial cells
Studies in experimental allergic encephalomyelitis, an animal model of multiple sclerosis (MS), suggest that astrocyte‐secreted… 
2001
2001
Characterisation of insulin-like growth factor-binding protein-3 binding to a novel receptor on human platelet membranes.
Insulin-like growth factor-binding protein-3 (IGFBP-3) is an important regulator of insulin-like growth factor (IGF… 
1998
1998
Is there a local IGF-system in human adrenocortical cells? 1 This study was supported by grant AL 332/2-1 and 2-2, Deutsche Forschungs-Gemeinschaft. 1
1998
1998
Effect of protein restriction on messenger RNA of insulin-like growth factor-I and insulin-like growth factor-binding proteins in liver of ovariectomized rats
Effects of dietary protein restriction and ovariectomy on plasma concentrations and hepatic messenger RNA (mRNA) of insulin-like… 
1997
1997
Effect of celiac disease and gluten-free diet on growth hormone-binding protein, insulin-like growth factor-I, and insulin-like growth factor-binding proteins.
Failure to thrive is common in children with celiac disease. As alterations in the growth hormone-insulin-like growth factor I… 
1997
1997
Surface‐bound plasmin induces selective proteolysis of insulin‐like‐growth‐factor (IGF)‐binding protein‐4 (IGFBP‐4) and promotes autocrine IGF‐II bio‐availability in human colon‐carcinoma cells
Limited proteolysis of insulin‐like‐growth‐factor (IGF)‐binding proteins (IGFBPs) represents a key process to modulate IGF bio… 
1996
1996
Cellular localization and sex steroid regulation of insulin-like growth factor binding protein messenger ribonucleic acids in the primate myometrium.
Insulin-like growth factors (IGF)-I and -II are abundant in the primate myometrium and are implicated in the sex steroid-induced… 
1995
1995
Periconceptual undernutrition resets plasma IGFBP levels and alters the response of IGFBP-1, IGFBP-3 and IGF-1 to subsequent maternal undernutrition in fetal sheep.
1993
1993
Insulin-like growth factor binding protein-4 gene expression is induced by transfection of gap junction connexin43 gene in a C6 glioma cell line.
When C6 glioma cells are stably transfected with a connexin43 cDNA and the gene overexpressed, the rate of cellular proliferation… 
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