Insulin-Like Growth Factor Binding Protein 4

Known as: Insulin Like Growth Factor Binding Protein 4, IGFBP-4, IGF Binding Protein 4 
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at… (More)
National Institutes of Health

Related topics

Related topics

11 relations
IGFBP4 geneIGFBP4 wt AlleleIn BloodProcess of secretion
(More)

Narrower (1)

Insulin-Like Growth Factor-Binding Protein 4, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
Insulin-like growth factor-1 as a vascular protective factor.
I. Insulin-Like Growth Factor-1 and Vascular Disease: Friend or Foe? The IGF-1 system is dynamic and complex,1,2 involving at… (More)
  • figure 1
  • figure 3
  • figure 2
Is this relevant?
2004
2004
Insulin-like growth factor binding protein-1-6 expression in activated microglia.
In the CNS insulin-like growth factor-1 (IGF-1) enhances survival of neurons, promotes myelin synthesis and acts as a mitogen for… (More)
Is this relevant?
2002
2002
Inhibition of Caco-2 cell proliferation by all-trans retinoic acid: role of insulin-like growth factor binding protein-6.
The present study examined the effects of all-trans retinoic acid (tRA) on proliferation and expression of the IGF system in Caco… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Evidence that IGF-binding protein-5 functions as a growth factor.
Recent studies support the concept that IGF-binding protein-5 (IGFBP-5) stimulates bone formation, at least in part, via IGF… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
1999
1999
Effects of recombinant insulin-like growth factor-binding protein-4 on bone formation parameters in mice.
Insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4), one of the most abundant IGFBPs produced by bone cells, is a potent… (More)
Is this relevant?
Review
1997
Review
1997
Serum insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 levels in aging and age-associated diseases
Because impaired bone formation is a major contributor to the pathogenesis of senile (type II) osteoporosis, and because insulin… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
Is this relevant?
1996
1996
Physiological role of insulin-like-growth-factor-binding protein-4 in human folliculogenesis.
Insulin-like growth factor (IGF)-I and IGF-II, and their binding proteins (IGFBPs) have been demonstrated to play important roles… (More)
Is this relevant?
1996
1996
Insulin-like growth factor-binding proteins produced by Vero cells, human oviductal cells and human endometrial cells, and the role of insulin-like growth factor-binding protein-3 in mouse embryo co…
Co-culturing embryos on helper cells can mimic the in-vivo environment, thereby enhancing embryo development in vitro. Insulin… (More)
Is this relevant?
1994
1994
Expression and insulin-like growth factor-dependent proteolysis of insulin-like growth factor-binding protein-4 are regulated by cell confluence in vascular smooth muscle cells.
Insulin-like growth factor (IGF)-I is markedly induced after balloon injury in the rat aorta, where it may serve to mediate… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
1993
1993
Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata.
Oestradiol is important in the growth of uterine leiomyomata and may act primarily or secondarily through mediators such as… (More)
Is this relevant?