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Insulin-Like Growth Factor Binding Protein 4

Known as: Insulin Like Growth Factor Binding Protein 4, IGFBP-4, IGF Binding Protein 4 
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at… 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The biological activity of IGF-I and -II is controlled by six binding proteins (IGFBPs), preventing the IGFs from interacting… 
Review
2004
Review
2004
Recent advances in cardiology have focused on proliferation and regeneration as potential cardiovascular defense mechanisms… 
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Review
2004
Review
2004
The insulin-like growth factor (IGF) system is an important regulator of bone formation. The IGFs (IGF-I and IGF-II) are the most… 
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Review
2004
Review
2004
  • L. Spicer
  • Biology of reproduction
  • 2004
  • Corpus ID: 24104448
Abstract This review summarizes evidence for the role of proteolytic enzymes that degrade and inactivate insulin-like growth… 
Highly Cited
2001
Highly Cited
2001
Insulin-like growth factors (IGFs) are important growth regulators of both normal and malignant prostate cells. Their action is… 
Highly Cited
2001
Highly Cited
2001
Pregnancy‐associated plasma protein‐A (PAPP‐A) has recently been identified as the proteinase responsible for cleavage of insulin… 
Highly Cited
1994
Highly Cited
1994
Previous studies have shown that the actions of insulin-like growth factor-II (IGF-II) in bone are determined by both its… 
Highly Cited
1994
Highly Cited
1994
Glucocorticoid (GC) modulates insulin-like growth factor (IGF) action in bone through mechanisms that are complex and not well… 
Highly Cited
1994
Highly Cited
1994
Primary osteoblast‐enriched (Ob) cultures from fetal rat bone synthesize insulinlike growth factor (IGF) I and IGF‐II, which each… 
Highly Cited
1992
Highly Cited
1992
Human fibroblasts secrete insulin-like growth factor-binding proteins (IGFBPs) that can modify insulin-like growth factor (IGF) I… 
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