Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Insulin-Like Growth Factor Binding Protein 4

Known as: Insulin Like Growth Factor Binding Protein 4, IGFBP-4, IGF Binding Protein 4 
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
The biological activity of IGF-I and -II is controlled by six binding proteins (IGFBPs), preventing the IGFs from interacting… Expand
Is this relevant?
2003
2003
BACKGROUND: Insulin-like growth factor (IGF) system components are important regulators of bone formation. Alterations of… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The IGF family plays an important role in implantation and placental physiology. IGF-II is abundantly expressed by placental… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Insulin-like growth factors (IGFs) are important growth regulators of both normal and malignant prostate cells. Their action is… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Pregnancy‐associated plasma protein‐A (PAPP‐A) has recently been identified as the proteinase responsible for cleavage of insulin… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Recent studies support the concept that IGF-binding protein-5 (IGFBP-5) stimulates bone formation, at least in part, via IGF… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Glucocorticoids inhibit the proliferation, but induce the differentiation, of bone marrow stromal cells into osteoblast-like… Expand
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Previous studies have shown that the actions of insulin-like growth factor-II (IGF-II) in bone are determined by both its… Expand
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Glucocorticoid (GC) modulates insulin-like growth factor (IGF) action in bone through mechanisms that are complex and not well… Expand
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Primary osteoblast-enriched (Ob) cultures from fetal rat bone synthesize insulin-like growth factor (IGF) I and IGF-II, which… Expand
Is this relevant?