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IGFBP4 gene

Known as: insulin like growth factor binding protein 4, INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 4, BP-4 
This gene plays a role in insulin-like growth factor modulation and cellular growth inhibition.
National Institutes of Health

Related topics

Related topics

8 relations
Homo sapiensIGFBP4 wt AlleleInhibition of Cell ProliferationInsulin-Like Growth Factor Binding Protein 4
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Development and validation of a spontaneous preterm delivery predictor in asymptomatic women.
BACKGROUND Preterm delivery remains the leading cause of perinatal mortality. Risk factors and biomarkers have traditionally… Expand
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Highly Cited
2013
Highly Cited
2013
Presence of UV filters in surface water and the effects of phenylbenzimidazole sulfonic acid on rainbow trout (Oncorhynchus mykiss) following a chronic toxicity test.
UV filters belong to a group of compounds that are used by humans and are present in municipal waste-waters, effluents from… Expand
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2002
2002
Identification of Estrogen‐Regulated Genes of Potential Importance for the Regulation of Trabecular Bone Mineral Density
Estrogen is of importance for the regulation of trabecular bone mineral density (BMD). The aim of this study was to search for… Expand
Highly Cited
2001
Highly Cited
2001
Systemic administration of insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) increases bone formation parameters in mice by increasing IGF bioavailability via an IGFBP-4 protease-dependent…
Insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) is a potent inhibitor of IGF actions in vitro. However, we found… Expand
Highly Cited
2000
Highly Cited
2000
Mammalian cell transformation and aneuploidy induced by five bisphenols
Bisphenol‐A (BP‐A), a monomer of plastics used in numerous consumer products and a xenoestrogen, induces cellular transformation… Expand
Highly Cited
1999
Highly Cited
1999
The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A.
Proteolytic cleavage of the six known insulin-like growth factor binding proteins (IGFBPs) is a powerful means of rapid structure… Expand
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1998
1998
A protease-resistant form of insulin-like growth factor (IGF) binding protein 4 inhibits IGF-1 actions.
Smooth muscle cells (SMC) secrete a serine protease that cleaves insulin-like growth factor (IGF) binding protein (IGFBP)-4 into… Expand
Highly Cited
1992
Highly Cited
1992
Endothelial cells express insulin-like growth factor-binding proteins 2 to 6.
Cultured endothelial cells have been shown to produce insulin-like growth factor-binding proteins (IGFBPs); however, the identity… Expand
Highly Cited
1991
Highly Cited
1991
Characterization of an insulin-like growth factor binding protein (IGFBP-4) produced by the B104 rat neuronal cell line: chemical and biological properties and differential synthesis by sublines.
A previous report from our laboratory described an approximately 30 kilodalton (kDa) insulin-like growth factor binding protein… Expand
Highly Cited
1991
Highly Cited
1991
Purification of a colon cancer cell growth inhibitor and its identification as an insulin-like growth factor binding protein.
We have purified a protein from serum-free conditioned medium of the HT29 human colon adenocarcinoma cell line based on its… Expand
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