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Paracrine Factors of Mesenchymal Stem Cells Recruit Macrophages and Endothelial Lineage Cells and Enhance Wound Healing
Bone marrow derived mesenchymal stem cells (BM-MSCs) have been shown to enhance wound healing; however, the mechanisms involved are barely understood. In this study, we examined paracrine factors… Expand
Mesenchymal Stem Cells Enhance Wound Healing Through Differentiation and Angiogenesis
Although chronic wounds are common, treatment for these disabling conditions remains limited and largely ineffective. In this study, we examined the benefit of bone marrow‐derived mesenchymal stem… Expand
Hypertrophic scars, keloids, and contractures. The cellular and molecular basis for therapy.
- E. Tredget, B. Nedelec, P. G. Scott, A. Ghahary
- The Surgical clinics of North America
- 1 June 1997
Keloids, hypertrophic scars, and contractures are a result of aberrations of the normal wound healing process. An understanding of the cellular and molecular events that are implicated in the… Expand
Peripheral Blood Fibrocytes from Burn Patients: Identification and Quantification of Fibrocytes in Adherent Cells Cultured from Peripheral Blood Mononuclear Cells
- L. Yang, P. G. Scott, J. Giuffre, H. Shankowsky, A. Ghahary, E. Tredget
- Laboratory Investigation
- 1 September 2002
Peripheral blood fibrocytes are a newly identified leukocyte subpopulation that displays fibroblast-like properties. These blood-borne cells can rapidly enter the site of injury at the same time as… Expand
Rating the resolving hypertrophic scar: comparison of the Vancouver Scar Scale and scar volume.
The increased focus of research interests and clinical documentation on outcomes demands that evaluation tools provide reliable and valid data. The Vancouver Scar Scale (VSS) was developed to provide… Expand
Fibrocytes from burn patients regulate the activities of fibroblasts
- J. Wang, H. Jiao, T. L. Stewart, H. Shankowsky, P. G. Scott, E. Tredget
- Wound repair and regeneration : official…
Wound healing requires an elaborate interplay between numerous cell types that orchestrate a series of regulated and overlapping events. Fibrocytes are a unique leukocyte subpopulation implicated in… Expand
Infection control in the burn unit.
The survival rates for burn patients have improved substantially in the past few decades due to advances in modern medical care in specialized burn centers. Burn wound infections are one of the most… Expand
Bladder outlet obstruction: progression from inflammation to fibrosis
Study Type – Aetiology (case control) Level of Evidence 3b
Predominance of staphylococcal organisms in infections occurring in a burns intensive care unit.
- G. Taylor, P. Kibsey, T. Kirkland, E. Burroughs, E. Tredget
- Burns : journal of the International Society for…
- 1 August 1992
To assess the sites, incidence, and bacteriology of infections in intensive care burn patients, a prospective survey of all admissions to a tertiary care institution burn unit was carried out over a… Expand
Cellular and molecular pathology of HTS: basis for treatment
Hypertrophic scar and keloids are fibroproliferative disorders of the skin which occur often unpredictably, following trauma and inflammation that compromise cosmesis and function and commonly recur… Expand