Iniparib

Known as: 4-iodo-3-nitrobenzamide, SAR240550 
A small molecule iodobenzamide with potential cytotoxic and antineoplastic activities. Although the mechanism of action is unknown, iniparib appears… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
0102019942017

Papers overview

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2015
2015
PURPOSE This study was designed to assess efficacy, safety, and predictors of response to iniparib in combination with… (More)
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2014
Highly Cited
2014
PURPOSE There is a lack of treatments providing survival benefit for patients with metastatic triple-negative breast cancer… (More)
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2012
Highly Cited
2012
PURPOSE Poly(ADP-ribose) polymerase (PARP) inhibitors are undergoing extensive clinical testing for their single-agent activity… (More)
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2012
2012
PURPOSE PARP inhibitors are being developed as therapeutic agents for cancer. More than six compounds have entered clinical… (More)
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2011
Highly Cited
2011
BACKGROUND Triple-negative breast cancers have inherent defects in DNA repair, making this cancer a rational target for therapy… (More)
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Highly Cited
2011
Highly Cited
2011
1007 Background: A randomized phase II study in mTNBC suggested that iniparib (I), an anticancer agent with PARP inhibitory… (More)
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2011
2011
Pancreatic cancer is an aggressive, frequently fatal malignancy that strikes 37,000 patients annually in the U.S.A. It is poorly… (More)
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2011
2011
n engl j med 364;18 nejm.org may 5, 2011 1780 rt-PA as a treatment strategy, which typically signals recurrent malfunction, with… (More)
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2010
2010
 
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1995
1995
A C-nitroso prodrug, 4-iodo-3-nitrobenzamide, was synthesized, and its action on a variety of tumor cells of human and animal… (More)
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