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Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds
It is shown that two such compounds, 3-nitrosobenzamide and 6-Nitroso-l,2-benzopyrone, inhibit infection of human immunodeficiency virus HIV- 1 in human lymphocytes and also eject zinc from isolated HIV-1 nucleocapsid zinc fingers and from intact HIV-2 virions.
Enzyme Inhibitors
Enzyme and Metabolic InhibitorsBy J. Leyden Webb. Vol. 2: Malonate, Analogs, Dehydroacetate, Sulfhydryl, 0-Iodosobenzoate, Mercurials. Pp. xx + 1237. 272s. Vol.3: Iodoacetate, Maleate. N
Regulation of the enzymatic catalysis of poly(ADP-ribose) polymerase by dsDNA, polyamines, Mg2+, Ca2+, histones H1 and H3, and ATP.
A novel regulation of PARP-1 activity and its chromatin-related functions by cellular bioenergetics is proposed that occurs in functional cells not exposed to catastrophic DNA damage.
The interaction of adenosine diphosphoribosyl transferase (ADPRT) with a cruciform DNA.
  • S. Sastry, E. Kun
  • Biology, Chemistry
    Biochemical and biophysical research…
  • 16 March 1990
Macromolecular enzymatic product of NAD+ in liver mitochondria.
Rat liver mitochondria contain a Mg2+-requiring system that transfers the ADP-ribose moiety of NAD+ to an acceptor protein, and identification of these products and reversibility of the reaction show that theADP- Ribosylated protein is the molecular species that is transferred to the acceptorprotein.
Studies on the Ehrlich ascites tumor. I. The enzymic and metabolic activities of the ascitic cells and the ascitic plasma.
The activity of a number of enzymes in homogenates of the tumor cells was studied, and mitochondria isolated from such preparations were shown to catalyze a marked uptake of inorganic phosphate concomitant with the oxidation of succinate.