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The coupling of O-pivaloyl benzhydroxamic acids with donor/acceptor diazo compounds provides isoindolones in high yield. The… Expand The alkylation of the ortho C-H bonds in benzamides and acrylamides containing an 8-aminoquinoline moiety as a bidentate… Expand The lack of robust and tunable chiral versions of cyclopentadienyl (Cp) ligands hampers progress in the development of catalytic… Expand The oxidative cycloaddition of benzamides and alkynes has been developed. The reaction utilizes Rh(III) catalysts in the presence… Expand A methodology for the high yield and facile synthesis of isoquinolones from benzamides and alkynes via the oxidative ortho C-H… Expand We report a mild and efficient Pd-catalyzed ortho-arylation of phenylacetamides, benzamides, and anilides with a range of simple… Expand The transition-metal-catalyzed functionalization of C-H bonds is a powerful method for generating carbon-carbon bonds. Although… Expand Several groups have provided evidence that positron emission tomography (PET) and single-photon emission computed tomography… Expand Serotonin is an important brain neurotransmitter that is relevant to depression, migraine, and other neuropsychiatric illnesses… Expand Schizophrenia is a major therapeutic challenge of modern medicine, and one of the last frontiers of brain research. The illness… Expand