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3-methoxybenzamide

Known as: benzamide, 3-methoxy- 
National Institutes of Health

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BenzamidesPoly(ADP-ribose) Polymerase Inhibitors

Papers overview

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2003
2003
1,5-isoquinolinediol increases the frequency of gene targeting by homologous recombination in mouse fibroblasts.
Gene targeting is a technique that allows the introduction of predefined alterations into chromosomal DNA. It involves a… 
1994
1994
Modification of glutamine synthetase in Streptomyces griseus by ADP-ribosylation and adenylylation.
Addition of NH4+ to STreptomyces griseus 2682 cells grown in NO3- containing medium resulted in a rapid decline in glutamine… 
1989
1989
Analgesic effects of 3‐methoxybenzamide in rats
Abstract— The i.p. injection of 3‐methoxybenzamide (3‐MBA) in rats produces a dose‐related elevation of the threshold for… 
1989
1989
Differential role for ADP-ribosylation in gene expression during the activation of T lymphocytes by various stimuli.
Simple competitive inhibitors of the nuclear enzyme ADP-ribosyltransferase, such as 3-methoxybenzamide (3MB), are known to block… 
1988
1988
Relationship of cellular oncogene expression to inhibition of growth and induction of differentiation of Daudi cells by interferons or TPA
Human α or β interferons inhibit the proliferation of Daudi Burkitt lymphoma cells and induce the differentiation of these cells… 
1988
1988
Inhibitors of ADP-ribosyl transferase suppress the mitogenic actions exerted by tumour promoters, but not those evoked by peptide mitogens, in primary neonatal rat hepatocytes.
A significant stimulation of the 24-h (between day 4 and 5 in vitro) new DNA synthetic activity was elicited in primary neonatal… 
1987
1987
Induction of B-cell differentiation antigens in interferon- or phorbol ester-treated Daudi cells is impaired by inhibitors of ADP-ribosyltransferase.
Treatment of the Daudi Burkitt lymphoma-derived cell line with human interferon alpha, which inhibits cell proliferation in this… 
1986
1986
[Spontaneous and induced sister chromatid exchanges in the blood lymphocytes of healthy persons and of xeroderma pigmentosum patients exposed to the inhibitors of DNA repair and replication caffeine…
The frequency of sister chromatid exchanges (SCEs), both spontaneous and induced by UV-light, X-rays, mitomycin C and… 
1985
1985
Potentiation of cell killing by inhibitors of poly(adenosine diphosphate-ribose) synthesis in bleomycin-treated Chinese hamster ovary cells.
Bleomycin-treated Chinese hamster ovary cells synthesize poly(adenosine diphosphate-ribose) in a reaction which is dose and time… 
1985
1985
Influence of poly(ADP-ribose) synthesis inhibitors on the repair of sublethal and potentially lethal damage in gamma-irradiated mammalian cells.
The influence of poly(ADP-ribose) synthesis inhibitors on mammalian cell radiosensitivity was investigated. Four different… 
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