PARP1 protein, human

Known as: ADPRT 1, Poly(ADP Ribose) Polymerase, NAD(+) ADP-Ribosyltransferase 1 
Poly [ADP-ribose] polymerase 1 (1013aa, ~113 kDa) is encoded by the human PARP1 gene. This protein is involved in poly ADP-ribosylation and in the… (More)

Topic mentions per year

Topic mentions per year

1976-2018
010020019762018

Papers overview

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Review
2014
Review
2014
Poly (ADP-ribose) polymerase-1 (PARP1) is an abundant, ubiquitously expressed NAD(+)-dependent nuclear enzyme that has prognostic… (More)
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Highly Cited
2011
Highly Cited
2011
SIRT1 regulates energy homeostasis by controlling the acetylation status and activity of a number of enzymes and transcriptional… (More)
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Highly Cited
2010
Highly Cited
2010
Research focused on the analysis and classification of breast tumors, primarily using DNA microarrays and patterns of gene… (More)
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Highly Cited
2008
Highly Cited
2008
CD133 (prominin-1), a 5-transmembrane glycoprotein, has recently been considered to be an important marker that represents the… (More)
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Highly Cited
2008
Highly Cited
2008
Nucleosome-binding proteins act to modulate the promoter chromatin architecture and transcription of target genes. We used… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE To evaluate the preclinical pharmacokinetics and antitumor efficacy of a novel orally bioavailable poly(ADP-ribose… (More)
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Highly Cited
2002
Highly Cited
2002
The DNA damage dependence of poly(ADP-ribose) polymerase-2 (PARP-2) activity is suggestive of its implication in genome… (More)
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Highly Cited
1998
Highly Cited
1998
We report that chlamydiae, which are obligate intracellular bacterial pathogens, possess a novel antiapoptotic mechanism… (More)
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Highly Cited
1998
Highly Cited
1998
Resveratrol, a constituent of grapes and other food products, has been shown to prevent carcinogenesis in murine models. We… (More)
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Highly Cited
1996
Highly Cited
1996
The DNA repair proteins XRCC1 and DNA ligase III are physically associated in human cells and directly interact in vitro and in… (More)
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