Poly(ADP-ribose) Polymerases

Known as: Poly(ADP-Ribose) Synthase, Poly(ADPribose) Polymerase, NAD(+) ADP ribosyltransferase 
Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
The discovery of poly(ADP-ribose) >50 years ago opened a new field, leading the way for the discovery of the poly(ADP-ribose… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
BACKGROUND Olaparib is a novel, orally active poly(ADP-ribose) polymerase (PARP) inhibitor that induces synthetic lethality in… (More)
  • figure 1
  • table 1
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2009
Highly Cited
2009
BACKGROUND The inhibition of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) is a potential synthetic lethal… (More)
  • table 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
2007
Highly Cited
2007
This corrects the article DOI: 10.1038/nature03443 
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Apoptotic and necrotic cell death are well characterized and are influenced by intracellular ATP levels. Poly(ADP-ribose… (More)
  • figure 2
  • figure 3
  • table 1
Is this relevant?
Highly Cited
1998
Highly Cited
1998
We have studied the apoptotic response of poly(ADP-ribose) polymerase (PARP)-/- cells to different inducers and the consequences… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Poly(ADP-ribose) polymerase [PARP; NAD+ ADP-ribosyltransferase; NAD+: poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
RECENT studies suggest that pro teases of the inter leukin 1-β-con-verting enzyme (ICE)/ced-3 family are involved in initiating… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Apoptosis is a morphologically and biochemically distinct form of cell death that occurs under a variety of physiological and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1992
Highly Cited
1992
THE abundant nuclear enzyme poly(ADP-ribose) polymerase catalyses the synthesis of poly(ADP-ribose) from nicotinamide adenine… (More)
Is this relevant?