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Ibogaine

Known as: Ibogaine [Chemical/Ingredient], 12-Methoxyibogamine, Ibogamine, 12-methoxy- 
One of several indole alkaloids extracted from Tabernanthe iboga, Baill. It has a complex pharmacological profile, and interacts with multiple… 
National Institutes of Health

Related topics

Related topics

27 relations

Narrower (12)

18-hydroxycoronaridine18-methoxycoronaridine20-desethyl-20-hydroxymethyl-11-demethoxyibogaine3'-hydroxyvoacamine

Broader (7)

AlkaloidsExcitatory Amino Acid AntagonistsHallucinogensIndoles
IBOGAINE HYDROCHLORIDEIn Bloodagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Thermostabilisation of the Serotonin Transporter in a Cocaine-Bound Conformation
2001
2001
Differential neuronal localizations and dynamics of phosphorylated and unphosphorylated type 1 inositol 1,4,5-trisphosphate receptors
Review
1998
Review
1998
Medication development of ibogaine as a pharmacotherapy for drug dependence.
The potential for deriving new psychotherapeutic medications from natural sources has led to renewal interest in rain forest… 
Review
1998
Review
1998
Mechanisms of antiaddictive actions of ibogaine.
Ibogaine, an alkaloid extracted from Tabemanthe iboga, is being studied as a potential long-acting treatment for oploid and… 
1997
1997
Ibogaine: a potent noncompetitive blocker of ganglionic/neuronal nicotinic receptors.
Ibogaine noncompetitively blocked (IC50 approximately 20 nM) 22NaCl influx through ganglionic-type nicotinic receptor channels of… 
Highly Cited
1996
Highly Cited
1996
18-Methoxycoronaridine, a non-toxic iboga alkaloid congener: effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats
Highly Cited
1995
Highly Cited
1995
Excitotoxic insult due to ibogaine leads to delayed induction of neuronal NOS in Purkinje cells
Ibogaine causes degeneration of Purkinje cells (PKCs), presumably via activation of neurons in the inferior olive leading to… 
1995
1995
Receptor binding profile suggests multiple mechanisms of action are responsible for ibogaine's putative anti-addictive activity
The indole alkaloid ibogaine (NIH 10567, Endabuse) is currently being examined for its potential utility in the treatment of… 
Highly Cited
1993
Highly Cited
1993
Ibogaine induces glial activation in parasagittal zones of the cerebellum.
Ibogaine, an indole alkaloid, has been proposed for treatment of drug addiction, yet its mechanism, site of action, and possible… 
1972
1972
Interaction of some centrally active drugs with caeruloplasmin.
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