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Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats
- J. Shoblock, Eric B. Sullivan, I. M. Maisonneuve, S. D. Glick
- Biology, PsychologyPsychopharmacology
- 1 February 2003
It is suggested that new pharmacotherapeutic agents that produce augmentations of NAC GLU or PFC DA activity, or perhaps inhibition of PFC GLU activity, may someday be useful for the treatment of METH addiction.
Kappa opioid inhibition of morphine and cocaine self-administration in rats
U50,488, a κ opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats
Effects and aftereffects of ibogaine on morphine self-administration in rats.
Anti-addictive actions of an iboga alkaloid congener: a novel mechanism for a novel treatment
18‐Methoxycoronaridine (18‐MC) and Ibogaine: Comparison of Antiaddictive Efficacy, Toxicity, and Mechanisms of Action
- S. D. Glick, I. M. Maisonneuve, K. Szumlinski
- BiologyAnnals of the New York Academy of Sciences
- 1 September 2000
The data suggest that 18‐MC has a narrower spectrum of actions and will have a substantially greater therapeutic index than ibogaine, and is likely to have an active metabolite.
Novel iboga alkaloid congeners block nicotinic receptors and reduce drug self-administration.
Comparative effects of dextromethorphan and dextrorphan on morphine, methamphetamine, and nicotine self-administration in rats.
Differences between d-methamphetamine and d-amphetamine in rats: working memory, tolerance, and extinction
These results indicate that METH and AMPH differ in altering working memory and the expression of tolerance, perhaps due to differences in behavioral inhibition.
Chronic administration of a cocaine "binge" alters basal extracellular levels in male rats: an in vivo microdialysis study.
- I. M. Maisonneuve, A. Ho, M. Kreek
- BiologyThe Journal of pharmacology and experimental…
- 1 February 1995
The acute tolerance phenomenon observed during an initial cocaine binge was abolished after chronic exposure and the cocaine "binge" on day 14 resulted in a lower elevation in extracellular DA levels than their corresponding values in saline-pretreated animals.